Anti-PIRT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss
BS-11623R-HRP
BOSSBS-11623R-HRPEA 900 EUR
BOSSBS-11623R-HRP
Anti-PIRT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Antibodies
PIRT is a 137 amino acid multi-pass membrane protein. Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain. Although PIRT is expressed in peripheral nervous system, with highest levels in dorsal root ganglion and trigeminal neurons, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord. PIRT is a required component of the VR1 complex, which positively regulates VR1, a sensor of both noxious heat and capsaicin. Correspondingly, PIRT knockout results in impaired responses toMore Product Information
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