Anti-ALKBH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss
BS-12565R-HRP
BOSSBS-12565R-HRPEA 900 EUR
BOSSBS-12565R-HRP
Anti-ALKBH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Antibodies
ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumorMore Product Information
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR