Anti-FHIT Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss
BS-1769R-A647
BOSSBS-1769R-A647EA 901 EUR
BOSSBS-1769R-A647
Anti-FHIT Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antibodies
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends onMore Product Information
Order Now

SPECIFICATIONS

Antigen symbol FHIT
Environmentally Preferable
Antigen name Fragile Histidine Triad
Antigen synonyms AP3Aase|FHIT |AP3AaseAP3A hydrolase|FRA3B
Antibody type Primary
Clonality Polyclonal
Conjugation Alexa Fluor® 647
Reactivity Human,Rat,Mouse
Host Rabbit
Gene ID 2272
Isotype IgG
ImmunoChemistry Yes
Immunogen 47-72/147
Form liquid
Purification Purified by Protein A
Concentration 1 μg/μl
Cross adsorption No
Storage buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature Store at 4°C for 12 months
Shipping temperature 4°C

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR