Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss
BS-2739R-CY5
BOSSBS-2739R-CY5EA 900 EUR
BOSSBS-2739R-CY5
Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)
Antibodies
PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKCMore Product Information
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