Anti-IKBKB Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss
BS-3232R-A488
BOSSBS-3232R-A488EA 921 EUR
BOSSBS-3232R-A488
Anti-IKBKB Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription ofMore Product Information
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