Anti-Importin 4 Rabbit Polyclonal Antibody

Supplier: Bioss
BS-7712R
BOSSBS-7712REA 725 EUR
BOSSBS-7712R
Anti-Importin 4 Rabbit Polyclonal Antibody
Antibodies
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. TheMore Product Information
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