Protein labelling reagent, iodoTMTzero™

Supplier: Thermo Fisher Scientific

90100
PIER90100EA 273 EUR
PIER90100
Protein labelling reagent, iodoTMTzero™
Protein Linking and Labeling Systems

The iodoTMTzero™ label reagent can be used as an isotopic 'light' duplex tag for MS-level protein quantitation.


  • Only reacts with sulfhydryl groups (reduced, unmodified cysteine residues), thus making it specific
  • Labeled proteins and peptides are not susceptible to reducing agents
  • Options for duplex isotopic (MS) or sixplex isobaric (MS/MS) quantitation
  • Can be used to study cysteine modifications (e.g. di-sulfide bridges, S-nitrosylation) making it versatile


This tag, along with the iodoTMTsixplex™ reagents can enable the quantitation of protein expression changes in cell-based and tissue samples that may not be amenable to metabolic isotopic labeling strategies (eg. SILAC).

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