You Searched For: 2-Bromo-6-methylpyridine


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Description: 8-Benzyl-2,8-diazaspiro[4.5]decan-3-one
Catalog Number: APOSOR952704-5G
UOM: 1 * 5 g
Supplier: Apollo Scientific


Description: 2-Phenyl-1,2,4-triazaspiro[4.5]decan-3-one 95%
Catalog Number: APOSOR32029-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 1-Phenyl-1,3,8-triazaspiro[4.5]decan-4-one 95+%
Catalog Number: APOSOR13975-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 8-Benzyl-1,3,8-triaza-spiro[4.5]decan-4-one
Catalog Number: APOSOR313002-250MG
UOM: 1 * 250 mg
Supplier: Apollo Scientific


Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC<sub>50</sub> = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.
Catalog Number: CAYM18372-5
UOM: 1 * 5 mg
Supplier: Cayman Chemical


Description: 5-Azaspiro[2.5]octan-8-one hydrochloride
Catalog Number: APOSOR935112-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 8-Benzyl-1-thia-4,8-diazaspiro[4.5]decan-3-one 95%
Catalog Number: APOSOR33505-5G
UOM: 1 * 5 g
Supplier: Apollo Scientific


Description: 8-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-thia-4,8-diazaspiro[4.5]decan-3-one
Catalog Number: APOSPC200237-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 1,4-Dioxaspiro[4.5]decan-8-ol 98%
Catalog Number: APOSOR46567-100G
UOM: 1 * 100 g
Supplier: Apollo Scientific


Description: 6-Azaspiro[2.5]octan-4-one hydrochloride
Catalog Number: APOSOR949325-250MG
UOM: 1 * 250 mg
Supplier: Apollo Scientific


Description: 1,4-Dioxaspiro[4.5]decan-8-ol ≥90%
Catalog Number: H26037.03
UOM: 1 * 1 g
Supplier: Thermo Fisher Scientific

Description: CAS No.: 22428-87-1
Catalog Number: ACRO241010050
UOM: 1 * 5 g
Supplier: Thermo Fisher Scientific

MSDS


Description: 7-Amino-2-azaspiro[4.4]nonan-3-one hydrochloride
Catalog Number: APOSOR304401-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: tert-Butyl-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate 97%
Catalog Number: APOSOR924090-5G
UOM: 1 * 5 g
Supplier: Apollo Scientific


Description: 9-Oxa-2-azaspiro[5.5]undecane
Catalog Number: APOSOR304433-5G
UOM: 1 * 5 g
Supplier: Apollo Scientific


Description: 6-Oxa-1-azaspiro[3.3]heptane hemioxalate 95%
Catalog Number: H57658.ME
UOM: 1 * 500 mg
Supplier: Thermo Fisher Scientific

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