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Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Catalog Number: BOSSBS-3398R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: BOSSBS-5537R-CY5
UOM: 1 * 100 µl
Supplier: Bioss


Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: BOSSBS-2739R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss


Description: Colourimetric and spectrophotometric substrate for detection of b-Galactosidase activity. ONPG is cleaved byb-Galactosidase via hydrolysis at the b-1-4-glycosidicbond between 2-nitrophenol and galactose.
Catalog Number: APOSBIM1202-10G
UOM: 1 * 10 g
Supplier: Apollo Scientific


Description: Acetobromo-alpha-D-glucuronic acid methyl ester 98%
Catalog Number: ACRO436290050
UOM: 1 * 5 g
Supplier: Thermo Fisher Scientific

MSDS


Description: α-Chloro-2-fluorotoulene ≥98%
Catalog Number: A11566.22
UOM: 1 * 100 g
Supplier: Thermo Fisher Scientific

Description: Providing a complete shelving unit in a single box, Convenience Pak™ shelving is the easy-to-order alternative to separate shelving components.
Unassembled Convenience Pak™ Each pack includes four shelves with split sleeves and four split posts with threaded connectors and leveling feet.
Catalog Number: 132-1428
UOM: 1 * 1 Each
Supplier: Metro International


Description: Stabilised with 2% calcium carbonate
Catalog Number: APOSBIA6200-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: β-galactosidase activator.
Catalog Number: ENZOALX582012G025
UOM: 1 * 25 g
Supplier: ENZO LIFE SCIENCES


Description: Isopropyl β-D-thiogalactopyranoside (IPTG) is derived from plant origin galactose.
Catalog Number: A7211.0025
UOM: 1 * 25 g
Supplier: PanReac AppliChem


Description: D-(+)-Maltose monohydrate
Catalog Number: A3891.1000
UOM: 1 * 1 kg
Supplier: PanReac AppliChem


Description: D-(+)-Raffinose pentahydrate ≥99%
Catalog Number: A18313.18
UOM: 1 * 50 g
Supplier: Thermo Fisher Scientific

Description: Thermo Scientific X-Gal (5-bromo-4-chloro-3-indolyl-beta-D-galacto-pyranoside) is an inert chromogenic substrate for beta-galactosidase which hydrolyzes X-Gal into colorless galactose and 4-chloro-3-brom-indigo, forming an intense blue precipitate
Catalog Number: R0404
UOM: 1 * 1 KIT
Supplier: Thermo Fisher Scientific

MSDS


Description: 2,3,6,2',3',4',6'-Hepta-O-acetyl-α-D-lactosyl bromide 98% min
Catalog Number: APOSBICL4047-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: N-Octyl-β-D-glucopyranoside
Catalog Number: DG015
UOM: 1 * 1 g
Supplier: G-Biosciences


Description: n-Dodecyl-β-D-maltoside 99%, high purity
Catalog Number: ACRO329370250
UOM: 1 * 25 g
Supplier: Thermo Fisher Scientific

MSDS


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