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Image Unavailable-BOSSBS-3582R-FITC

Anti-T1 gamma Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Catalog Number: BOSSBS-3582R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3418R-CY7

Anti-SMAD1 + SMAD5 Rabbit Polyclonal Antibody (Cy7®)

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Catalog Number: BOSSBS-3418R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3418R-A350

Anti-SMAD1 + SMAD5 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Catalog Number: BOSSBS-3418R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10380R-A488

Anti-SMAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Catalog Number: BOSSBS-10380R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10380R-A647

Anti-SMAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Catalog Number: BOSSBS-10380R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10381R-HRP

Anti-SMAD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Catalog Number: BOSSBS-10381R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-6117R-HRP

Anti-TR1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
Catalog Number: BOSSBS-6117R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0699R-A647

Anti-SLC33A1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
Catalog Number: BOSSBS-0699R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0699R-CY5.5

Anti-SLC33A1 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
Catalog Number: BOSSBS-0699R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0699R-CY7

Anti-SLC33A1 Rabbit Polyclonal Antibody (Cy7®)

Description: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
Catalog Number: BOSSBS-0699R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-1778R-A647

Anti-GATA4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Catalog Number: BOSSBS-1778R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-1778R-A680

Anti-GATA4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Catalog Number: BOSSBS-1778R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-BRDY170387

Accessories for label printers EMEA, M211

Description: M211 Hard case
Catalog Number: BRDY170387
UOM: 1 * 1 items
Supplier: Brady
Product Image-BRDY177233

Barcode Scanner, V4500

Description: A rugged design offering seamless experience. Digitise data capture and automate your workflows with ease and accuracy with the V4500 Barcode Scanner.
Catalog Number: BRDY177233
UOM: 1 * 1 items
Supplier: Brady

New Product


Product Image-MFLX75501-12

Flexible Impeller Self-Priming Non-Metallic Pumps

Description: Pumps fluids in applications where durability is needed—the 12 VDC models are ideal for remote/portable use.
Catalog Number: MFLX75501-12
UOM: 1 * 1 items
Supplier: Avantor Fluid Handling

CE Compliant


Image Unavailable-BOSSBS-3860R-A647

Anti-CHRDL2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
Catalog Number: BOSSBS-3860R-A647
UOM: 1 * 100 µl
Supplier: Bioss
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