Amphotericin B

Supplier: Thermo Scientific
Warning

Synonyms: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid

J61491.MC J61491.03 J61491.06
J61491.MCEA 79.5 EUR
J61491.MC J61491.03 J61491.06
Amphotericin B
Amphotericin B

Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus.


  • Moisture and light sensitive


Amphotericin B trihydrate was observed to cause suppression of bone marrow progenitor cells and to induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro.


Yellow powder


Soluble in aqueous buffers at pH 2.0 or 11.0. Insoluble at pH 6.0-7.0. Also soluble in DMSO or DMF

Formula: C₄₇H₇₃NO₁₇
MW: 924,08 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00877763
CAS Number: 1397-89-3
EINECS: 215-742-2
Merck Index: 14,585

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