Anti-TYMS Mouse Monoclonal Antibody (CF640R) [clone: TS106]

Supplier: Biotium
BNC400714-500 BNC400714-100
BNC400714-500EA 560 EUR
BNC400714-500 BNC400714-100
Anti-TYMS Mouse Monoclonal Antibody (CF640R) [clone: TS106]
Antibodies
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. ExpressionMore Product Information
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR