Anti-CNN1 Mouse Monoclonal Antibody (Biotin) [clone: CALP CNN1/832]

Supplier: Biotium
BNCB0833-500 BNCB0833-100
BNCB0833-500EA 560 EUR
BNCB0833-500 BNCB0833-100
Anti-CNN1 Mouse Monoclonal Antibody (Biotin) [clone: CALP CNN1/832]
Antibodies
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

Type: Primary
Antigen: CNN1
Clonality: Monoclonal
Clone: CALP CNN1/832
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human, Rat
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