BAM15 ≥98%, crystalline solid
Supplier: Cayman Chemical
Synonyms:
BAM 15, N5,N6-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
BAM15 is a mitochondrial protonophore uncoupler which increase proton transport into the mitochondrial matrix through an ATP synthase-independent pathway, thereby uncoupling nutrient oxidation from ATP production.
- High oxygen flux than FCCP
These are used to determine rate of cellular respiration and have antioxidant effects that protect from ischemia-reperfusion injury. The off target activity of this uncouplers leads to the undesired effects, including plasma membrane depolarization, mitochondrial inhibition, and cytotoxicity.
Formula:
C₁₆H₁₀F₂N₆O MW: 340,29 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00373912 CAS Number: 210302-17-3 |
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