Amphotericin B
Supplier: BIOWEST
Synonyms:
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Amphotericin B used in tissue culture to prevent growth of yeasts and fungi. It changes the function and integrity of eucaryotic cell membranes by forming complexes with sterols (cholesterol) hence having no effect on bacteria. Cause leakage of glucose.
- Yellow coloured, with a pH of 10 – 11,5
- Shelf life of 24 month
Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Caution: This product is intended to be used in vitro, in laboratory only. Not recommended to be used in therapy, human or veterinary applications.
Formula:
C₄₇H₇₃NO₁₇ MW: 924,08 g/mol |
MDL Number:
MFCD00877763 CAS Number: 1397-89-3 |
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