1400W dihydrochloride ≥98%

Supplier: ENZO LIFE SCIENCES AG

Synonyms: 1400W 2HCl, N-(3-(Aminomethyl)benzyl)acetimidamide dihydrochloride

ALX270073M005 ALX270073M025
ENZOALX270073M005EA 93.5 EUR
ENZOALX270073M005 ENZOALX270073M025
1400W dihydrochloride ≥98%
1400W dihydrochloride

iNOS inhibitor


A slow, tight binding and highly selective inhibitor of inducible nitric oxide synthase (iNOS/NOS II) in vitro and in vivo. Binds tightly to iNOS with a Kd of 7nM. In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with Ki values of 2 and 50µM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices.

Formula: C₁₀H₁₅N₃·2HCl
MW: 250,167 g/mol
MDL Number: MFCD03428622
CAS Number: 214358-33-5

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