Anti-CD73 Mouse Monoclonal Antibody [clone: AD2] (APC)

Supplier: STEMCELL Technologies
60044AZ 60044AZ.1
STMC60044AZEA 717 EUR
STMC60044AZ STMC60044AZ.1
Anti-CD73 Mouse Monoclonal Antibody [clone: AD2] (APC)
Antibodies
Mouse monoclonal IgG1 antibody against human, rhesus, chimpanzee CD73, APC-conjugated.

  • Mesenchymal stem
  • Progenitor cells

The AD2 antibody reacts with human CD73, a glycosyl phosphatidylinositol (GPI)-anchored glycoprotein and ecto-5’-nucleotidase expressed on the surface of subsets of B and T cells, follicular dendritic cells, mesenchymal stem cells, endothelial cells, and epithelial cells. CD73 catalyzes the hydrolysis of 5’-adenosine monophosphate (AMP) to form the bioactive nucleoside adenosine, and plays a pivotal role in the activation of P1 adenosine receptors by regulating extracellular adenosine concentrations. CD73 also appears to function as a co-signaling molecule on T cells and as an adhesion molecule mediating lymphocyte interactions with the endothelium and follicular dendritic cells. CD73 is used as a marker for lymphocyte differentiation, its expression increasing during development. It is also a useful marker for identifying undifferentiated mesenchymal stem cells. CD73 is highly expressed in many types of human and mouse cancers, and has been implicated in the control of tumor growth.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-CD73 Mouse Monoclonal Antibody [clone: AD2] (APC)
Antigen: CD73
Clonality: Monoclonal
Clone: AD2
Conjugation: APC
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chimpanzee, Human, Macaque, Rhesus monkey
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR