Human/Mouse/Rat Recombinant Activin-A (from E. coli)

Supplier: Shenandoah Biotechnology

800-01-100UG 800-01-10UG 800-01-1MG 800-01-500UG
SHBT800-01-100UGEA 584 EUR
SHBT800-01-100UG SHBT800-01-10UG SHBT800-01-1MG SHBT800-01-500UG
Human/Mouse/Rat Recombinant Activin-A (from E. coli)
Proteins and Peptides

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin βA chains. Cleavage of the N-terminal propeptide renders the Activin protein biologically active. Human Activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline Activin A proteins.


  • High Quality
  • Low Endotoxin
  • Affordable


Caution: For research use only.

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SPECIFICATIONS

Protein/peptide name Activin-A
Environmentally Preferable
Protein synonyms Inhibin beta-1|FRP|FSH-releasing protein
Protein/peptide type Recombinant
Protein function Cytokine
Species Human,Rat,Mouse
Source E. coli
Conjugation Unconjugated
Gene ID P08476 / Q04998 / P18331
Sequence MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
Protease-free N
Animal-free N
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤0,1
Biological activity Bioactivity assay: Cytotoxicity of MPC-11 cells, ED50 ≤10 ng/ml, Bioactivity ≥1,0×10⁵ units/mg
Purity ≥95%
Grade RUO
Formulation 0,1% Trifluoroacetic Acid (TFA)
Molecular weight 13,1/26,2 kDa
Reconstitution instructions Sterile water at 0.1 mg/ml
Storage conditions At or below –20 °C
Shipping temperature RT
Tested applications Bioassay

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