all-rac-α-Tocopherol 96.0-102.0%, EMPROVE® ESSENTIAL Ph. Eur., BP, USP, E307, SAFC®
Supplier: MERCK PRODUCTION CHEMICALS
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Warning
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Synonyms:
(±)-α-Tocopherol, Vitamin E Alcohol, all-rac-α-Tocopherol, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol, DL-alpha-Tocopherol, Vitamin E
Corresponds to Ph. Eur., BP, USP, E 307
Conforms to the purity criteria on food additives according to the current European Commission Regulation.
# specified acc. to EMEA/CHMP/SWP/4446/2000 (Specification limits for residues of metal catalysts or metal reagents).
Other residues of metal catalysts or metal reagents acc. to this guideline are not likely to be present.
Formula:
C₂₉H₅₀O₂ MW: 430,71 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00072051 CAS Number: 10191-41-0 EINECS: 233-466-0 |
Specification Test Results
Assay (GC, Ph. Eur.) | 96.0 - 102.0 % |
Assay (GC, USP) | 96.0 - 102.0 % |
Identity (IR) | conforms |
Identity (GC) | conforms |
Identity (colour reaction) | conforms |
Appearance | clear, colourless to yellow-brownish, viscous, oily liquid; almost odourless |
Acidity | conforms |
Optical rotation α 20/D (100 g/l; anhydrous ethanol) | -0.01 - 0.01 ° |
Optical rotation α 25/D (100 g/l; chloroforme) | -0.05 - 0.05 ° |
Refractive index (n 20/D) | 1.503 - 1.507 |
Spec. Absorptivity A 1%/1cm (292 nm; 0,1 g/l, anhydrous ethanol) | 72 - 76 |
Spec. Absorptivity A1%/1cm (292 nm; 0,05 g/l , anhydrous Ethanol) | 71 - 76 |
Heavy metals (as Pb) | ≤ 10 ppm |
As (Arsenic) | ≤ 3 ppm |
Cu (Copper) | ≤ 10 ppm |
Hg (Mercury) | ≤ 1 ppm |
Pb (Lead) | ≤ 2 ppm |
Zn (Zinc)# | ≤ 25 ppm |
Heptane (HS-GC) | ≤ 5000 ppm |
Methanol (HS-GC) | ≤ 3000 ppm |
Pyridine (HS-GC) | ≤ 200 ppm |
Toluene (HS-GC) | ≤ 890 ppm |
Other residual solvents (ICH Q3C) | excluded by manucfacturing process |
Related substances (Ph. Eur., impurity A) | ≤ 0.5 % |
Related substances (Ph. Eur., impurity B) | ≤ 1.5 % |
Related substances (Ph. Eur., sum of impurities C and D) | ≤ 1.0 % |
Related substances (Ph. Eur., any other impurity) | ≤ 0.25 % |
Related substances (Ph. Eur., total impurities) | ≤ 2.5 % |
Sulfated ash (600 °C) | ≤ 0.1 % |
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