all-rac-α-Tocopheryl acetate (Vitamin E acetate), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, FCC, SAFC®

Supplier: MERCK PRODUCTION CHEMICALS

Synonyms: (±)-α-Tocopherol acetate, all-rac-α-Tocopheryl acetate, Vitamine E acetate, DL-alpha-Tocopheryl acetate, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl acetate

5.00952.0100 5.00952.5000
5.00952.0100EA 350 EUR
5.00952.0100 5.00952.5000
all-rac-α-Tocopheryl acetate (Vitamin E acetate), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, FCC, SAFC®
DL-α-Tocopherol acetate

Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Corresponds to Ph. Eur., BP, USP, FCC

Formula: C₃₁H₅₂O₃
MW: 472,75 g/mol
MDL Number: MFCD00072042
CAS Number: 7695-91-2
EINECS: 231-710-0

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Specification Test Results

Assay (GC, Ph. Eur.) 96.5 - 102.0 %
Assay (GC, USP) 96.0 - 102.0 %
Assay (GC, FCC) 960 - 1020 I.U./g
Identity (IR) conforms
Optical rotation α 20/D (100 g/l; anhydrous ethanol) -0.01 - 0.01 °
As (Arsenic) ≤ 0.0003 %
Cu (Copper) ≤ 0.0025 %
Pb (Lead) ≤ 0.0002 %
Zn (Zinc) ≤ 0.0010 %
Acetic acid (HS-GC) ≤ 5000 ppm
Heptane (HS-GC) ≤ 5000 ppm
Methanol (HS-GC) ≤ 3000 ppm
Pyridine (HS-GC) ≤ 200 ppm
Toluene (HS-GC) ≤ 890 ppm
Other residual solvents (ICH Q3C) excluded by manucfacturing process
Related substances (Ph. Eur., impurity A) ≤ 0.5 %
Related substances (Ph. Eur., impurity B) ≤ 1.5 %
Related substances (Ph. Eur., impurity C) ≤ 0.5 %
Related substances (Ph. Eur., sum of impurities D and E) ≤ 1.0 %
Related substances (Ph. Eur., any other impurity) ≤ 0.25 %
Related substances (Ph. Eur., total impurities) ≤ 2.5 %
Acidity conforms

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