Disodium hydrogen phosphate, anhydrous 98.0-100.5% (by acidometric titration), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, JPE, E339, SAFC®

Supplier: MERCK PRODUCTION CHEMICALS

Synonyms: sec-Sodium phosphate, di-Sodium hydrogen orthophosphate, di-Sodium hydrogen phosphate anhydrous, Sodium hydrogen phosphate, Disodium phosphate, Sodium phosphate dibasic

1.06585.5000 1.06585.1000
1.06585.5000EA 534 EUR
1.06585.5000 1.06585.1000
Disodium hydrogen phosphate, anhydrous 98.0-100.5% (by acidometric titration), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, JPE, E339, SAFC®
di-Sodium hydrogen phosphate

Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).


Certifications: Corresponds to Ph Eur, BP, USP, JPE, E 339
Conforms to the purity criteria on food additives according to the current European Commission Regulation.

Formula: Na₂HPO₄
MW: 141,96 g/mol
Melting Pt: 250 °C
Density: 1,53 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00003496
CAS Number: 7558-79-4
EINECS: 231-448-7
REACH: 01-2119489797-11
Merck Index: 12,08805

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Specification Test Results

Assay (calculated on dried substance according to Ph Eur) 98.0 - 101.0 %
Assay (calculated on dried substance according to USP) 98.0 - 100.5 %
Assay (acidimetric; dried substance) 99.0 - 101.0 %
Identity passes test
Appearance of solution passes test
In water insoluble matter (calculated on dried substance) ≤ 0.20 %
Sodium dihydrogen phosphate (NaH₂PO₄) ≤ 1.7 %
pH-value (1 %, water) 9.0 - 9.4
Carbonate passes test
Chloride (Cl) ≤ 0.01 %
Fluoride (F) ≤ 0.001 %
Sulfate (SO₄) ≤ 0.03 %
Heavy metals (as Pb) ≤ 0.001 %
As (Arsenic) ≤ 0.0001 %
Cd (Cadmium) ≤ 0.0001 %
Fe (Iron) ≤ 0.002 %
Hg (Mercury) ≤ 0.0001 %
Ni (Nickel)* ≤ 0.0002
Pb (Lead) ≤ 0.0001 %
Residual solvents (ICH Q3C) excluded by production process
Substances reducing potassium permanganate passes test
Loss on drying (130 °C) ≤ 1.0 %
Particle size (< 0.315 mm) about 99 %

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