4-(Dimethylamino)cinnamaldehyde chromogenic reagent for indoles and flavanols, Sigma-Aldrich®

Supplier: SIGMA-ALDRICH MICROSCOPY
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Synonyms: p-Dimethylamino-Cinnamaldehyde

M-Clarity™ quality level = MQ200

D4506-10G D4506-1G D4506-25G D4506-5G
D4506-10GEA 275 EUR
D4506-10G D4506-1G D4506-25G D4506-5G
4-(Dimethylamino)cinnamaldehyde chromogenic reagent for indoles and flavanols, Sigma-Aldrich®
4-(Dimethylamino)cinnamaldehyde

Reagent for assay of indole product of apotryptophanase and tryptophanase. DMAC produces colored adducts with flavanols for subsequent HPLC. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.


  • 4-(Dimethylamino)cinnamaldehyde (DMAC) has been used in the serine protease inhibition assay
  • It has been used for the detection of (epi)-flavan-3-ols and proanthocyanidin polymers in Brassica napus seeds
  • It has been used for the determination of phenolic compounds in leaf samples
  • It has been used for the staining of flavan-3-ols in plant samples

Formula: C₁₁H₁₃NO
MW: 175.23 g/mol
Melting Pt: 138,..140 °C (lit.)
Storage Temperature: Freezer
MDL Number: MFCD00007002
CAS Number: 6203-18-5
EINECS: 228-267-0
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Specification Test Results

Appearance (colour) Yellow to very dark yellow and orange to very dark orange
Appearance (form) Powder
Purity (HPLC area %) ≥97.5 %
Solubility (colour) Yellow to very dark yellow to very dark red
Solubility (turbidity) Clear to hazy
Solubility (method) 250 mg in 5 ml chloroform/ethanol (1:1)
Proton nmr spectrum Conforms to structure
Recommended retest period 48 months

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