You Searched For: 2,3-Butanediol

Catalog Number: (BOSSBS-5358R-FITC)

Supplier: Bioss

Description: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5357R-HRP)

Supplier: Bioss

Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-4112R-HRP)

Supplier: Bioss

Description: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3766R-A488)

Supplier: Bioss

Description: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3766R-A680)

Supplier: Bioss

Description: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-13261R-HRP)

Supplier: Bioss

Description: The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-13260R-HRP)

Supplier: Bioss

Description: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-13261R-A350)

Supplier: Bioss

Description: The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.

UOM: 1 * 100 µl

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Catalog Number: (ABNOPAB14537)

Supplier: Abnova

Description: Rabbit polyclonal antibody raised against synthetic peptide of Gabrg2.

UOM: 1 * 50 µl

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Catalog Number: (ORIGTA328815)

Supplier: OriGene

Description: Anti-Gabra4 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

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Catalog Number: (ANTIA17286-100)

Supplier: ANTIBODIES.COM

Description: Anti-GABRA4 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Catalog Number: (ABNOPAB9686)

Supplier: Abnova

Description: Rabbit polyclonal antibody raised against a recombinant Gabrb2.

UOM: 1 * 100 µG

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Supplier: Abcam

Description: Rabbit monoclonal [EPR25323-127] to GABRB3 - BSA and Azide free.

Supplier: Abcam

Description: Rabbit monoclonal [EPR24328A-120] to GALR2 - BSA and Azide free.

Catalog Number: (BOSSBS-12064R-A750)

Supplier: Bioss

Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyse the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R©1-3, GABAA R∂ GABAA R gamma, GABAA R delta 1 and GABAA R delta 2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.

UOM: 1 * 100 µl

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Catalog Number: (ABNOPAB26185)

Supplier: Abnova

Description: Rabbit polyclonal antibody raised against synthetic peptide of GALR3.

UOM: 1 * 50 µG

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