You Searched For: \\u03B1-Ketoglutaric+acid+disodium+salt+hydrate


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Catalog Number: (BOSSBS-9634R-A350)
Supplier: Bioss
Description: The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ?ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ?ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Ca2+ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg2+. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock. IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.
UOM: 1 * 100 µl


Supplier: Thermo Fisher Scientific
Description: 1-Pentanesulphonic acid sodium salt monohydrate 98+% for HPLC
Catalog Number: (ACRO401180250)
Supplier: Thermo Fisher Scientific
Description: Methyl blue, pure, certified
UOM: 1 * 25 g

Supplier: Honeywell Chemicals
Description: Sodium thiosulphate 0.2 M Na2S2O3 (0.2N) volumetric solution, Fluka™

Supplier: Honeywell Chemicals
Description: Sodium thiosulphate 0.05 M Na2S2O3 (0.05N) volumetric solution, Fluka™
Catalog Number: (HACH32332)
Supplier: Hach
Description: Sodium thiosulphate 0.1 mol/l (0.1 N) in aqueous solution
UOM: 1 * 100 mL

Supplier: Thermo Fisher Scientific
Description: 1-Heptanesulphonic acid sodium salt monohydrate for HPLC
Supplier: Thermo Fisher Scientific
Description: Sodium thiosulphate standardised solution 0.1 N in aqueous solution
Supplier: PanReac AppliChem
Description: Sodium metabisulphite USP, NF, BP, Ph. Eur., pure
Supplier: AAT BIOQUEST
Description: EDANS sodium salt is much more water-soluble than EDANS acid.

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Catalog Number: (ROTHX869.1)
Supplier: Roth Carl
Description: Sodium thiosulphate 0.01 mol/l (0.01 N) in aqueous solution
UOM: 1 * 1 L

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (HACH2408949)
Supplier: Hach
Description: Sodium thiosulphate 0.0109 mol/l (0.0109 N) in aqueous solution
UOM: 1 * 500 mL


Catalog Number: (MOLE44541922-500G)
Supplier: Molekula
Description: EDTA dipotassium salt dihydrate
UOM: 1 * 500 g

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (Q0501-10MG)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Calcium-specific chelator and indicator. Upon binding calcium there is a shift in the UV spectrum and an enhancement of fluorescence.
UOM: 1 * 10 mg


Catalog Number: (E772-25G)
Supplier: VWR Chemicals
Description: Bluish-green dye that is soluble in alcohol. Can be used with safranin as a stain for plant tissue and for demonstrating nuclear histones.
UOM: 1 * 25 g

Supplier: Biotium
Description: This antibody recognizes a 45 kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, formingalpha-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production ofalpha-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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