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Image Unavailable-BOSSBS-3251R-FITC

Anti-ALOX5 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Catalog Number: BOSSBS-3251R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ROTH4717.1

Arachidonic acid

Description: Arachidonic acid
Catalog Number: ROTH4717.1
UOM: 1 * 100 mg
Supplier: Roth Carl
Image Unavailable-BOSSBS-3251R-A680

Anti-5-Lipoxygenase Ser271 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyses the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Catalog Number: BOSSBS-3251R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12999R

Anti-DGKE Rabbit Polyclonal Antibody

Description: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.
Catalog Number: BOSSBS-12999R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ENZOBMLEI1170100

RO 20-1724 ≥99% (by TLC)

Description: Selective, potent cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50=2µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells.
Catalog Number: ENZOBMLEI1170100
UOM: 1 * 100 mg
Supplier: ENZO LIFE SCIENCES
Image Unavailable-BOSSBS-0420R-A350

Anti-PIBF1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
Catalog Number: BOSSBS-0420R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ENZOBMLCN2050010

8-Br-cGMP ≥96% (by HPLC)

Description: A cell-permeable cGMP analog which is more resistant to phosphodiesterases than cGMP and which preferentially activates cGMP-dependent protein kinase. It inhibits thrombin stimulated arachidonic acid release in human platelets.
Catalog Number: ENZOBMLCN2050010
UOM: 1 * 10 mg
Supplier: ENZO LIFE SCIENCES
Image Unavailable-USBIA1359-76J

Anti-ALOX5AP Rabbit Polyclonal Antibody

Description: Anti-ALOX5AP Rabbit Polyclonal Antibody
Catalog Number: USBIA1359-76J
UOM: 1 * 50 µl
Supplier: US Biological
Image Unavailable-BOSSBS-0420R-CY7

Anti-PIBF1 Rabbit Polyclonal Antibody (Cy7®)

Description: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
Catalog Number: BOSSBS-0420R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12999R-CY3

Anti-DGKE Rabbit Polyclonal Antibody (Cy3®)

Description: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.
Catalog Number: BOSSBS-12999R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12999R-CY5

Anti-DGKE Rabbit Polyclonal Antibody (Cy5®)

Description: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.
Catalog Number: BOSSBS-12999R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ENZOBMLL1220001

Bis(methylthio)gliotoxin ≥99% (by TLC)

Description: Inhibits PAF-induced platelet aggregation (IC50=8.4 µM) and collagen-induced aggregation (IC50=84.2 µM) with no effect on arachidonic acid or ADP induced aggregation. Inhibits PAF-induced bronchoconstriction in vivo in the guinea-pig (69% at 1.0 mg/kg).
Catalog Number: ENZOBMLL1220001
UOM: 1 * 1 mg
Supplier: ENZO LIFE SCIENCES
Image Unavailable-BOSSBS-3251R

Anti-ALOX5 Rabbit Polyclonal Antibody

Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Catalog Number: BOSSBS-3251R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3251R-A555

Anti-ALOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Catalog Number: BOSSBS-3251R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ENZOBMLST3350010

AACOCF3 ≥98% (by TLC)

Description: AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid amide hydrolase (100% at 7.5 µM).
Catalog Number: ENZOBMLST3350010
UOM: 1 * 10 mg
Supplier: ENZO LIFE SCIENCES
Image Unavailable-BOSSBS-5060R-A555

Anti-TAAR8 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids from precursor essential polyunsaturated fatty acids, linoleic acid and alphanlinolenic acid. It catalyzes the desaturation of dihomo gamma linoleic acid and eicosatetraenoic acid to generate arachidonic acid and eicosapentaenoic acid respectively.
Catalog Number: BOSSBS-5060R-A555
UOM: 1 * 100 µl
Supplier: Bioss
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