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Image Unavailable-HAWKZ11000

Counting chamber, McMaster

Catalog Number: (HAWKZ11000)
Supplier: HAWKSLEY AND SONS
Description: Counting chamber with cover glass and two counting areas.
UOM: 1 * 1 items
Product Image-215-0284

Dispenser Bottles

Supplier: SEMADENI
Description: Bottles, LDPE, for quick dispensing, with PMP measuring cup. The 25 /50 ml measuring cup slides up and down the tube. The height of the tube determines the volume of liquid dispensed into the measuring cup when the bottle is squeezed.

Product Image-631-1127

Counting chambers, Fuchs-Rosenthal

Supplier: LABOR OPTIK
Description: Sixteen large squares of 1 mm² each. Each large square is divided into 16 small squares.

Product Image-LOVI56B000701

Dipslide incubator, DI 10

Catalog Number: (LOVI56B000701)
Supplier: Lovibond
Description: The DI 10 incubator is designed for reliable incubation of bacteriological slides, on-site, in a laboratory or even while mobile in a car or van.
UOM: 1 * 1 items
Product Image-MOTIP31S

Inverted microscopes, AE31E

Catalog Number: (MOTIP31S)
Supplier: MOTIC
Description: The AE31E has been designed with an extended focus for practical aspects.
UOM: 1 * 1 items
Product Image-135-1717

Biological safety cabinets, class II, BioVanguard Green Line

Supplier: CleanAir by Baker
Description: BioVanguard Green Line is a Class II cabinet range which offers simplicity, robustness and high reliability and ensures the highest level of protection for the operator, product and environment, minimising the hazards inherent with working with agents assigned to biosafety levels one, two and three. It is designed for microbiological research with biological agents (e.g. bacteria, viruses, etc) and allergens.

Product Image-BRND473100

Staining troughs with lid

Supplier: Brand
Description: Soda-lime glass.

Image Unavailable-RUBBFG360088WHT

Ingredient Bin Slant

Catalog Number: (RUBBFG360088WHT)
Supplier: Rubbermaid Commercial Products
Description: The Rubbermaid commercial ProSave® ingredient and food storage mobile bin is a bulk food storage container on wheels. With a slanted front, sliding opening, and 32-ounce scoop, these food storage containers make it easy to transport ingredients.
UOM: 1 * 1 items

New Product


Product Image-HERA1950799

Racks for sliding drawer freezer, Matrix, Matrix 2D and Nunc CryoBank

Supplier: Thermo Scientific
Description: Maximise tube storage capacity per freezer with Thermo Scientific™ Sliding drawer racks for tubes (4 inner door freezers), a racking solution for four inner-door, ultra-low temperature freezers. Use in conjunction with Thermo Scientific™ dense storage vials.

Image Unavailable-1.00778.0001

Accessories

Catalog Number: (1.00778.0001)
Supplier: Merck
Description: Compact Benchtop Incubator, Cult-Dip combi, dip culture media
UOM: 1 * 10 items

MSDS Certificates


Product Image-ROCK600-401-D20

Anti-COL1A1 Rabbit Polyclonal Antibody

Catalog Number: (ROCK600-401-D20)
Supplier: Rockland Immunochemicals
Description: Anti-Collagen 1 alpha 1 telopeptide Antibody is suitable for use in ELISA, Western Blotting and IHC. The antibody works well for IHC on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90° C.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3804R-A488

Anti-MSH6 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-3804R-A488)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3804R-A680

Anti-MSH6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3804R-A680)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and Recognises single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0758R-A488

Anti-MSH2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-0758R-A488)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0758R-CY7

Anti-MSH2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0758R-CY7)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0758R-A647

Anti-MSH2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-0758R-A647)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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