You Searched For: 2-Deoxy-D(-)-ribose

Catalog Number: (BOSSBS-0084R-CY5.5)

Supplier: Bioss

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

UOM: 1 * 100 µl

Sale

Supplier: Apollo Scientific

Description: 1,6-Anhydro-2-deoxy-2-fluoro-β-D-glucopyranose ≥99%

Supplier: Apollo Scientific

Description: 2-Fluoro-4-nitrophenyl 2-azido-2-deoxy-β-D-galactopyranoside 95%

Supplier: Apollo Scientific

Description: Methyl 2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranoside ≥98%

Supplier: Apollo Scientific

Description: Benzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside ≥98%

Catalog Number: (BOSSBS-9623R-FITC)

Supplier: Bioss

Description: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-9623R-A555)

Supplier: Bioss

Description: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.

UOM: 1 * 100 µl

Sale

Supplier: Apollo Scientific

Description: 1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate 98%

Supplier: Apollo Scientific

Description: 1-O-Acetyl-2-deoxy-3,5-di-O-benzoylribofuranose

Catalog Number: (PRSI36-169)

Supplier: ProSci Inc.

Description: Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair and is associated with the negatively charged polymer of adenosine 5'-diphosphate (ADP)-ribose (PAR). PAR is synthesized from nicotinamide adenine dinucleotide (NAD+) by the poly(ADP-ribose) polymerase protein family (PARPs), of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks. PARP-1 is selectively activated by DNA strand breaks to catalyze the addition of long branched chains of PAR to a variety of nuclear proteins, most notably PARP itself. The amount of PAR formed in living cells with DNA damage is commensurate with the extent of the damage. Under DNA damage conditions, PAR undergoes a rapid turnover, with a half-life in the range of minutes, as PAR is rapidly hydrolyzed and converted to free ADP-ribose by the enzyme poly(ADP-ribose)glycohydrolase (PARG). PAR regulates not only cell survival and cell-death programmes, but also an increasing number of other biological functions with which novel members of the PARP family have been associated. These include transcriptional regulation, cell division, intracellular trafficking, inflammation and energy metabolism.

UOM: 1 * 100 µG

Sale

Supplier: Apollo Scientific

Description: 2-Chloro-4-nitrophenyl 2-azido-2-deoxy-β-D-galactopyranoside 95%

Supplier: Apollo Scientific

Description: 2,4-Dinitrophenyl 2-deoxy-2-fluoro-β-D-glucopyranoside ≥98%

Supplier: Apollo Scientific

Description: Fluorescent substrate for N-acetyl-b-D-galactosaminidase.

Supplier: Apollo Scientific

Description: 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine (2’-FANA-G) ≥97%

Supplier: Apollo Scientific

Description: 1,6-Anhydro-2-azido-2-deoxy-β-D-glucopyranose ≥99%

Supplier: Apollo Scientific

Description: Methyl 3-amino-3-deoxy-α-D-mannopyranoside hydrochloride ≥98%