You Searched For: 2-Deoxy-D(-)-ribose

Catalog Number: (PRSI36-169)

Supplier: ProSci Inc.

Description: Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair and is associated with the negatively charged polymer of adenosine 5'-diphosphate (ADP)-ribose (PAR). PAR is synthesized from nicotinamide adenine dinucleotide (NAD+) by the poly(ADP-ribose) polymerase protein family (PARPs), of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks. PARP-1 is selectively activated by DNA strand breaks to catalyze the addition of long branched chains of PAR to a variety of nuclear proteins, most notably PARP itself. The amount of PAR formed in living cells with DNA damage is commensurate with the extent of the damage. Under DNA damage conditions, PAR undergoes a rapid turnover, with a half-life in the range of minutes, as PAR is rapidly hydrolyzed and converted to free ADP-ribose by the enzyme poly(ADP-ribose)glycohydrolase (PARG). PAR regulates not only cell survival and cell-death programmes, but also an increasing number of other biological functions with which novel members of the PARP family have been associated. These include transcriptional regulation, cell division, intracellular trafficking, inflammation and energy metabolism.

UOM: 1 * 100 µG

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Supplier: Apollo Scientific

Description: 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)adenine (FANA-A) ≥98%

Supplier: Apollo Scientific

Description: 1,6-Anhydro-2-azido-2-deoxy-β-D-glucopyranose ≥99%

Supplier: Apollo Scientific

Description: 3-O-Acetyl-1,6-anhydro-2-azido-2',3'-di-O-benzyl-4',6'-O-benzylidene-2-deoxy-β-D-cellobiose ≥98%

Supplier: Apollo Scientific

Description: Phosphorylated in vivo & transported across cell membranes, where it enters the metabolic cycle in a similar fashion to glucose but does not complete the cycle.

Supplier: Apollo Scientific

Description: 2,6-Anhydro-3-deoxy-D-glycero-D-galacto-non-2-enoic acid ≥98%

Supplier: Apollo Scientific

Description: Benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside ≥98%

Supplier: Apollo Scientific

Description: Methyl 3-amino-3-deoxy-α-D-mannopyranoside hydrochloride ≥98%

Supplier: Apollo Scientific

Description: Methyl 3-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-β-D-galactopyranoside ≥98%

Supplier: Apollo Scientific

Description: Methyl 3-O-benzyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranoside ≥99%

Catalog Number: (MOLE23543542-1G)

Supplier: Molekula

Description: L(+)-Ribose

UOM: 1 * 1 g

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Catalog Number: (APOSBICY1065-1MG)

Supplier: Apollo Scientific

Description: 6-deoxy-6-((2-carboxyethyl)sulphinyl)-heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gamma-cyclodextrin ammonium/ sodium mixed salt

UOM: 1 * 1 mg

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Supplier: Apollo Scientific

Description: (E)-2-Acetamido-3,4,6-tri-O-benzoyl-2-deoxy-D-glucose 1-oxime ≥98%

Supplier: Apollo Scientific

Description: Methyl 2,3,4-tri-O-acetyl-6-azido-6-deoxy-α-D-glucopyranoside ≥98%

Supplier: Apollo Scientific

Description: 1,6-Di-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-α-D-glucopyranose ≥99%

Catalog Number: (BOSSBS-0151R-CY7)

Supplier: Bioss

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

UOM: 1 * 100 µl

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