You Searched For: 6-Benzyloxyindole-3-carbaldehyde


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Description: High vacuum stopcocks, Witaflo-red are made of borosilicate glass.
Catalog Number: WITG0.290.203
UOM: 1 * 1 items
Supplier: witeg Labortechnik


Description: Borosilicate glass, clear, narrow neck.
Catalog Number: WITG5.611.005
UOM: 1 * 1 items
Supplier: witeg Labortechnik


Description: Glass vessel for two-piece 500 ml reactor without parts for bottom drain valve.
Catalog Number: METB51162631
UOM: 1 * 500 mL
Supplier: Mettler - Toledo

New Product


Description: Flexible discharge tube with recirculation valve, for Varispenser 2 (x) with nominal volume of 2 ml, 5 ml or 10 ml, For: Varispenser/Varispenser plus and Top Buret dispensor
Catalog Number: EPPE4966502.008
UOM: 1 * 1 SET
Supplier: EPPENDORF


Description: These in-line MicroFilters effectively protect columns from particles originating in the mobile phase or sample, or from pump seal and sample injection valve wear.
Catalog Number: UPCHM-140
UOM: 1 * 5 items
Supplier: UPCHURCH SCIENTIFIC


Description: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
Catalog Number: BOSSBS-9474R-HRP
UOM: 1 * 100 µl
Supplier: Bioss


Description: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
Catalog Number: BOSSBS-9474R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localised to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localisation signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
Catalog Number: BOSSBS-9474R-A750
UOM: 1 * 100 µl
Supplier: Bioss


Description: Atypical chemokine receptor that controls chemokine levels and localisation via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalising receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
Catalog Number: BOSSBS-15371R-HRP
UOM: 1 * 100 µl
Supplier: Bioss


Description: Chemically resistant diaphragm pump with frequency changer and gas ballast valve. Suction-side separator with 500 ml round-bottomed flask.
Catalog Number: ILMV116264
UOM: 1 * 1 items
Supplier: Welch by Gardner Denver


Description: Made of fracture-proof and food-safe polyethylene with sleeve connection for a hose.
Catalog Number: HUEN520705
UOM: 1 * 1 items
Supplier: hünersdorff GmbH

New Product


Description: Steel cylinder, valve fitted with safety locking handwheel, 3,0 litre, 200 bar for total duration of 15 minutes, 5 kg, ∅ 110 mm x length: 375 mm, fully charged, for short duration breathing apparatus Cen-Paq, Cen-Paq
Catalog Number: SCTS1046044
UOM: 1 * 1 items
Supplier: SCOTT SAFETY


Description: The ChromasterUltra Rs is the result of many years of research, development and experience, leading to the introduction of one of the most advanced, robust and easy to use UHPLC system available on the market today. Hitachi-High Technologies is a world leader in fluid control and optical analysis technology, as well as in high performance electronics. Hitachi has focused on combining the knowledge of these three key disciplines to give the world of chromatography one of the best instruments for today's demands. To arrange a demonstration with one of our experts, please email chromatography@eu.vwr.com.
Catalog Number: 903-0373
UOM: 1 * 1 items
Supplier: VWR Collection


Description: The burner is constructed with a gas control needle valve. Specially designed conical mixing chamber is incorporated, which allows the burner to give off a very hot flame.
Catalog Number: 4010/2
UOM: 1 * 1 items
Supplier: R L ENTERPRISES


Description: DURAN®, borosilicate glass 3.3, clear, with PTFE spindle.
Catalog Number: 201-1320
UOM: 1 * 1 items
Supplier: DWK Life Sciences


Description: Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.
Catalog Number: BOSSBS-9474R-A488
UOM: 1 * 100 µl
Supplier: Bioss


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