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Image Unavailable-BOSSBS-5537R-CY5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-5537R-CY5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2739R-CY5.5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2739R-CY5.5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-APOSBIMB1008-5G

IPTG (isopropyl-β-D-thiogalactopyranoside) ≥99% dioxane-free

Supplier: Apollo Scientific
Description: IPTG is used in conjunction with X-Gal for detection of lac+ colonies or cells in a colorimetric assay to detect recombinants (white) from non-recombinants (blue) in cloning strategies.

Product Image-437132J

X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside) ≥98.0%

Catalog Number: (437132J)
Supplier: VWR Chemicals
Description: X-Gal is a chromogenic substrate for ß-Galactosidase that forms an intense blue precipitate. Used in conjunction with IPTG in a colorimetric assay, X-Gal allows differentiation of recombinants from non recombinants in cloning experiments with vectors containing the lacZ gene. It is also used in microbiology to detect microorganisms which have ß-Galactosidase activity.
UOM: 1 * 1 g

MSDS Certificates


Image Unavailable-APOSBIM1013-250MG

Maltohexaose

Supplier: Apollo Scientific
Description: Maltohexaose

Image Unavailable-BOSSBS-3132R-CY5.5

Anti-BMX Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-3132R-CY5.5)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3132R-CY3

Anti-BMX Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-3132R-CY3)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3132R-HRP

Anti-BMX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-3132R-HRP)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3132R-A488

Anti-BMX Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-3132R-A488)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5223R-CY3

Anti-BMX Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5223R-CY3)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2765R-CY5

Anti-BMX Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-2765R-CY5)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5537R-CY3

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5537R-CY3)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-R0402

X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside) enzyme substrate

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific X-Gal (5-bromo-4-chloro-3-indolyl-beta-D-galacto-pyranoside) is an inert chromogenic substrate for beta-galactosidase which hydrolyzes X-Gal into colorless galactose and 4-chloro-3-brom-indigo, forming an intense blue precipitate

Image Unavailable-CAYM20797-500

Isomaltose ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Isomaltose is a glucose disaccharide with an α-(1 - 6) linkage, as opposed to the α-(1 - 4) linkage found in maltose. It can be liberated from dextran by dextranase and is hydrolyzed to D-glucose by isomaltase through an α-D-glucosidase-type action. Congenital sucrase-isomaltase deficiency is a rare autosomal intestinal disorder resulting from mutations affecting the gene encoding, the proprotein from which sucrase and isomaltase are produced.

Certificates

Image Unavailable-APOSBIMB1001-10G

X-Gal (5-bromo-4-chloro-3-indolyl-ß-D-galactopyranoside) ≥98%

Supplier: Apollo Scientific
Description: X-Gal, a chromogenic substrate of beta-Galactosidase. Used in conjunction with IPTG for detection of beta-Galactosidase activity in bacterial colonies in a colorimetric assay.

Image Unavailable-APOSBIMB1075-1G

N-Octyl-β-D-glucopyranoside ≥99%, Ultrapure

Supplier: Apollo Scientific
Description: Non-ionic detergent used for membrane protein solubisation. An advantage of OG is its low molecular weight which allows easy removal by dialysis.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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