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Supplier: GILSON
Description: SupaTop syringe filters offer reliable and cost-effective solutions for particles removal and clarification needs.

Supplier: Bohlender
Description: Reusable clamps with PTFE-encapsulated steel spring core for connecting ground joint parts.

Supplier: Merck
Description: Filters for sterilising or clarifying biological solutions. The larger filtration area increases flow rate and throughput. It also makes it easier to filter solutions because it reduces the pressure required to empty the syringe.

Supplier: Trajan Scientific and Medical
Description: Needle, Gauge: 25, Length: 50 mm, Ø ext.: 0,50 mm, Type of tip: Side hole/dome, N25/500-5H

Catalog Number: (BOSSBS-13330R-CY3)
Supplier: Bioss
Description: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13333R-CY3)
Supplier: Bioss
Description: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-8276R-CY5)
Supplier: Bioss
Description: G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/actions, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. GRIN2 (G protein-regulated inducer of neurite outgrowth 2), also known as GPRIN2, is a 458 amino acid protein that is expressed in cerebellum and is thought to play a role in neurite outgrowth. GRIN2 interacts with activated G?oand G?, and is encoded by a gene that maps to human chromosome 10q11.22.
UOM: 1 * 100 µl


Catalog Number: (LOVI366110)
Supplier: Lovibond
Description: Plastic syringe, 1 ml
UOM: 1 * 1 items


Supplier: BELLINGHAM STANLEY
Description: Accessory for density meter, Filling syringes, 5 ml

Supplier: Cytiva (Formerly Pall Lab)
Description: Useful for prefiltration of particulate laden aqueous samples, serum filtration and dissolution testing.

Environmentally Preferable

Supplier: Trajan Scientific and Medical
Description: Constructed from borosilicate glass, PTFE plunger tips and Kel-F® or PTFE Luer cones where applicable.

Catalog Number: (006660.)
Supplier: Trajan Scientific and Medical
Description: Syringe, chromatography, HPLC, Gas-tight, with PTFE-tipped plunger, 1/4-28 UNF front thread, 250C-THERMOSPEC, Volume: 250 µl, For: AS100/300 and AS1000/3000/3500 LC autosamplers, Pk: 1
UOM: 1 * 1 items


Catalog Number: (BOSSBS-8275R-CY5)
Supplier: Bioss
Description: GPRIN1 may be involved in neurite outgrowth.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13333R-CY5)
Supplier: Bioss
Description: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13328R-CY3)
Supplier: Bioss
Description: Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13328R-CY5)
Supplier: Bioss
Description: Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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