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You Searched For: 5-Bromo-2-methoxy-nicotinic+acid


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Human recombinant NMNAT3 (highly active) (from E. coli)

Catalog Number: (PRSI90-357)
Supplier: ProSci Inc.
Description: Mitochondrial NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyses the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.
UOM: 1 * 50 µG
Image Unavailable-APOSBISN0276-25MG

PH-797804

Catalog Number: (APOSBISN0276-25MG)
Supplier: Apollo Scientific
Description: MAPK/ERK Signalling Pathway
UOM: 1 * 25 mg
Image Unavailable-APOSOR8075-1G

Methyl-4-bromo-3-methoxythiophene-2-carboxylate 97%

Supplier: Apollo Scientific
Description: Methyl-4-bromo-3-methoxythiophene-2-carboxylate 97%

Image Unavailable-PRSI90-356

Human recombinant NMNAT3 (highly active) (from E. coli)

Catalog Number: (PRSI90-356)
Supplier: ProSci Inc.
Description: Mitochondrial NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyses the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.
UOM: 1 * 10 µG
Product Image-PRSI30-467

Anti-NMNAT1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI30-467)
Supplier: ProSci Inc.
Description: The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).
UOM: 1 * 100 µG
Image Unavailable-65361-250MG

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, Supelco®

Catalog Number: (65361-250MG)
Supplier: Merck
Description: (R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, Supelco®
UOM: 1 * 250 mg
Image Unavailable-65369-250MG-F

(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, Supelco®

Catalog Number: (65369-250MG-F)
Supplier: Merck
Description: (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, Supelco®
UOM: 1 * 250 mg
Image Unavailable-APOSBISN0131-5MG

Bedaquiline

Supplier: Apollo Scientific
Description: Bedaquiline, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Certificates

Image Unavailable-8.20877.0100

(S)-(-)-Nicotine for synthesis, Sigma-Aldrich®

Supplier: Merck
Description: (S)-(-)-Nicotine for synthesis, Sigma-Aldrich®

MSDS

Image Unavailable-PRSI90-354

Human recombinant NMNAT1 (highly active) (from E. coli)

Catalog Number: (PRSI90-354)
Supplier: ProSci Inc.
Description: Nuclear NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
UOM: 1 * 10 µG
Image Unavailable-PRSI90-355

Human recombinant NMNAT1 (highly active) (from E. coli)

Catalog Number: (PRSI90-355)
Supplier: ProSci Inc.
Description: Nuclear NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
UOM: 1 * 50 µG
Image Unavailable-PRSI91-237

Human recombinant QAPRTase (from E. coli)

Catalog Number: (PRSI91-237)
Supplier: ProSci Inc.
Description: Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
UOM: 1 * 50 µG
Image Unavailable-A12398.22

(S)-(-)-Nicotine ≥99%

Supplier: Thermo Fisher Scientific
Description: (S)-(-)-Nicotine ≥99%

MSDS Certificates

Image Unavailable-65365-100MG-F

(+)-ɑ-Methoxy-ɑ-(trifluoromethyl)phenylacetyl chloride ≥99.0%, LiChropur™ for chiral derivatisation, Supelco®

Supplier: Merck
Description: (R)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride (Mosher’s acid chloride) is generally used as a chiral derivatizing agent.

Image Unavailable-65363-500MG

(-)-ɑ-Methoxy-ɑ-(trifluoromethyl)phenylacetyl chloride ≥99.0%, LiChropur™ for chiral derivatisation, Supelco®

Supplier: Merck
Description: (R)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride (Mosher’s acid chloride) is generally used as a chiral derivatizing agent.

Image Unavailable-APOSOR4771-5G

2-Methoxy-5-pyrimidineboronic acid

Supplier: Apollo Scientific
Description: 2-Methoxy-5-pyrimidineboronic acid

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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