You Searched For: 6-Bromo-L-tryptophan

Catalog Number: (BOSSBS-10125R-A555)

Supplier: Bioss

Description: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-10125R-A350)

Supplier: Bioss

Description: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

UOM: 1 * 100 µl

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Catalog Number: (ROCK612-401-E48)

Supplier: Rockland Immunochemicals

Description: Anti-Trytophan Hydroxylase pS19 (Rabbit) antibody is suitable for use in Western Blotting. Expect a band of approximately 55 kDa in size corresponding to tryptophan hydroxylase Protein phosphorylated at Ser 19 in the appropriate cell lysate or extract.

UOM: 1 * 100 µl

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Catalog Number: (USBI031354)

Supplier: US Biological

Description: Anti-Coronin 1a Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Catalog Number: (ROCK600-401-E49)

Supplier: Rockland Immunochemicals

Description: Anti-Tryptophan Hydroxylase pS260 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of 55 kDa in size corresponding to typtophan hydroxylase Protein phosphorylated at Ser 260.

UOM: 1 * 100 µl

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Catalog Number: (PRSI90-358)

Supplier: ProSci Inc.

Description: The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species. The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, <i>Anopheles gambiae</i>.

UOM: 1 * 50 µG

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Catalog Number: (PRSIXPS-1030)

Supplier: ProSci Inc.

Description: Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CAM K II). Both PKA and CAM K II phosphorylate Ser58 which lies within the regulatory domain of TPH.

UOM: 1 * 100 µl

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Catalog Number: (GEMB800-120-050)

Supplier: GEMINI BIO-PRODUCTS

Description: This diagnostic-grade product is an aqueous solution containing 25% human albumin (w/v). It is prepared by cold-alcohol fractionation from pooled human plasma obtained from venous blood. The USP Pharmacopeia requires that all fractionators add sodium caprylate and sodium tryptophanate as a preservative.

UOM: 1 * 50 mL

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Catalog Number: (GEMB800-121-050)

Supplier: GEMINI BIO-PRODUCTS

Description: This diagnostic-grade product is an aqueous solution containing 20% human albumin (w/v). It is prepared by cold-alcohol fractionation from pooled human plasma obtained from venous blood. The USP Pharmacopeia requires that all fractionators add sodium caprylate and sodium tryptophanate as a preservative.

UOM: 1 * 50 mL

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Catalog Number: (BOSSBS-10125R-CY3)

Supplier: Bioss

Description: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-10125R-CY7)

Supplier: Bioss

Description: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

UOM: 1 * 100 µl

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Catalog Number: (PRSI50-242)

Supplier: ProSci Inc.

Description: Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin) (Martinez et al., 2001). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II) (Jiang et al., 2000; Johansen et al., 1996). CaM K II phosphorylates Ser19 which lies within the regulatory domain of TPH2 (McKinney et

UOM: 1 * 100 µl

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Catalog Number: (PRSI28-013)

Supplier: ProSci Inc.

Description: Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.

UOM: 1 * 50 µG

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Catalog Number: (PRSI91-280)

Supplier: ProSci Inc.

Description: There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.

UOM: 1 * 50 µG

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Catalog Number: (ROCK600-601-C96)

Supplier: Rockland Immunochemicals

Description: Anti-Tryptophan Hydroxylase (Sheep) antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size.

UOM: 1 * 100 µl

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Catalog Number: (USBI0014-07E)

Supplier: US Biological

Description: Anti-14-3-3 gamma Mouse Monoclonal Antibody [clone: 9A70]

UOM: 1 * 100 µl

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