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Product Image-730-0408

Precast agarose gels, RunOne™

Description: RunOne™ precast gels do not require a specific gel apparatus but are optimised for use with the RunOne™ Electrophoresis System. A choice of 100, 104 or 108 well formats make these gels convenient for all screening applications.
Catalog Number: 730-0408
UOM: 1 * 5 items
Supplier: EMBITEC
Product Image-KIML774261-0005

Stopper, rubber, plug-type, KIMBLE®

Description: These stopper fits into the neck of the apparatus. Ideal for outgassing NMR tubes, pressure venting and addition of reactants via syringes.
Catalog Number: KIML774261-0005
UOM: 1 * 50 items
Supplier: KIMBLEKONTES
Product Image-MFLX77200-60

Masterflex® L/S® Easy-Load® II Pump Heads for Precision Tubing, Avantor®

Description: Automatic retention holds tubing securely in place with no manual adjustment—just load the tubing and start the pump.
Catalog Number: MFLX77200-60
UOM: 1 * 1 items
Supplier: Avantor Fluid Handling

ISO9001 2 year warranty


Image Unavailable-WHEA123753

Distillation glassware set with standard taper 19/22 Clear-Seal® joints, Micro Kit®, WHEATON®

Description: Manufactured from WHEATON 33 low extractable borosilicate glass that conforms to USP Type I and ASTM E 438 Type I, Class A requirements.
Catalog Number: WHEA123753
UOM: 1 * 1 items
Supplier: DWK Life Sciences
Image Unavailable-BOSSBS-1402R-A680

Anti-SREBP-1/2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
Catalog Number: BOSSBS-1402R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-1402R-A647

Anti-SREBP-1/2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
Catalog Number: BOSSBS-1402R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-MFLX07015-52

Masterflex® L/S® Standard Pump Heads for High-Performance Precision Tubing, Avantor®

Description: Ideal for fluid transfer applications requiring high accuracy and repeatability.
Catalog Number: MFLX07015-52
UOM: 1 * 1 items
Supplier: Avantor Fluid Handling

2 year warranty


Product Image-BURK9768-0002

Hand protectors, HotGrip

Description: The cold and heat resistant HotGrip protectors are made of silicone rubber. They protect fingers and hands from burns and freezing when working with apparatus that have extreme temperatures from −60 to +200 °C (briefly up to +250 °C).
Catalog Number: BURK9768-0002
UOM: 1 * 1 items
Supplier: BURKLE
Product Image-MFLX07591-20-UK

Masterflex® I/P® Digital Modular Drive with Remote Input/Output, Avantor®

Description: Place motor and controller where convenient with modular design.
Catalog Number: MFLX07591-20-UK
UOM: 1 * 1 items
Supplier: Avantor Fluid Handling

CE Compliant 2 year warranty


Product Image-MFLX07514-32

Masterflex® L/S® Easy-Load® Pump Heads for High-Performance Precision Tubing, Avantor®

Description: Save time with fast tubing changes and reduced maintenance.
Catalog Number: MFLX07514-32
UOM: 1 * 1 items
Supplier: Avantor Fluid Handling

2 year warranty


Image Unavailable-PRSI33-983

Anti-ACTA2 Mouse Monoclonal Antibody [clone: SMAT2-1]

Description: Actins are a family of proteins which are highly conserved and play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. [RefSeq].
Catalog Number: PRSI33-983
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Image Unavailable-BOSSBS-13492R-A488

Anti-GORASP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
Catalog Number: BOSSBS-13492R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13492R-CY7

Anti-GORASP2 Rabbit Polyclonal Antibody (Cy7®)

Description: The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
Catalog Number: BOSSBS-13492R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0022R-CY5.5

Anti-MAPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis.
Catalog Number: BOSSBS-0022R-CY5.5
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-PRSI6049

Anti-SYNPO Rabbit Polyclonal Antibody

Description: SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
Catalog Number: PRSI6049
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-HICHHI-726

VWR® Hichrom Nuts and Ferrules

Description: Precision-machined stainless steel nuts and ferrules.
Catalog Number: HICHHI-726
UOM: 1 * 10 items
Supplier: Avantor
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