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Catalog Number: (ENZOBMLAK5160001)
Supplier: ENZO LIFE SCIENCES
Description: A Fluor-de-Lys® fluorescent assay system. The HDAC6 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC6 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions. The Fluor de Lys® HDAC6 assay is based on the Fluor de Lys® Substrate and Fluor de Lys® Developer combination. The assay procedure has two steps. First, the Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with HDAC6. Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the Fluor de Lys®Developer produces a fluorophore.
UOM: 1 * 1 KIT

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Supplier: Thermo Fisher Scientific
Description: B-PER® Bacterial Protein Extraction Reagents are designed to extract soluble protein from bacterial cells. The B-PER® Bacterial Protein Extraction Kit eliminates the need for harsh mechanical procedures, like sonication. The easy-to-use cell lysis solution uses mild non-ionic detergents to disrupt cells and solubilise proteins without denaturation. Enzyme supplements such as DNase I and Lysozyme allow for improved yield of large molecular weight proteins which are difficult to purify. B-PER® is also compatible with downstream protein purification methods such as GST purification and His-tagged immobilised metal affinity chromatography (IMAC).

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Supplier: Avantor
Description: These Vydac MS columns are a later development from Grace for the reversed phase HPLC separation of biomolecules. A proprietary surface treatment and bonding process gives Vydac MS columns a unique selectivity. A variety of reversed phases makes this product line suitable for the analysis of small peptides to large intact, undenatured proteins.

Catalog Number: (ROCKKAA064)
Supplier: Rockland Immunochemicals
Description: These assays are non-radioactive methods for detecting specific transcription factor DNA binding activity in nuclear extracts and whole cell lysates. A specific dsDNA sequence containing the NF[kappa]B response element is immobilized on the bottom of the wells in a 96-well plate. The transcription factor is detected by the addition of a specific primary antibody. A colorimetric readout at 450 nm is obtained through a horseradish peroxidase-conjugated secondary antibody.
UOM: 1 * 1 KIT


Supplier: Avantor
Description: Vydac TP was the first range of wide pore media phases developed in the Vydac range and became the industry standard for peptide and protein separations. The large pores of the 300 Å TP silica give polypeptide molecules complete access to the interior of the silica pores.

Supplier: Brady
Description: V1300 power supply kit, with V1300 cradle, V1200 battery, AC adapter, power cable, USB cable for V4500, Brady®, For: V4500

New Product

Supplier: MP Biomedicals
Description: Deoxyribonucleic acid sodium salt has been used in a study to evaluate the cytotoxicity of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin. Deoxyribonucleic acid sodium salt has also been used in a study to develop a simple method for extracting DNA from Cryptosporidium oocysts.

Supplier: THERMO SCIENTIFIC MAYBRIDGE
Description: The Maybridge portfolio consists of high-quality hit-like, lead-like and drug-like compounds which can generate valuable data in screening programs. They are developed specifically to support the pharmaceutical drug discovery process.

Supplier: VWR Chemicals
Description: These solutions are developed and produced according to chapter 2.2.2. 'Degree of colouration of liquids' of the European Pharmacopoeia. (brown, brown-yellow, green-yellow, red and yellow). These kits are ready to use, and are dedicated to help you save time and money because preparation of these solutions is very complex.
Supplier: Biosensis
Description: The oligomeric form of Amyloid Beta peptide (Aβ, 1- 42) has been closely linked to Alzheimer’s Disease. Several ELISAs targeting Aβ have been developed; however, these ELISAs are known to cross-react with Amyloid Beta precursor protein (APP) and are poorly characterised against monomeric and oligomeric forms of the peptide.

Catalog Number: (MMMA601)
Supplier: 3M
Description: For an alternative method to sharing a probed fit testing respirator, use the 3M™ quantitative fit test adapter. The adaptor kits allow users to fit test with a personal 3M™ Respirator, rather than using a shared probed fit test respirator.
UOM: 1 * 1 items


Supplier: Avantor
Description: Vydac TP was the first range of wide pore media phases developed in the Vydac range and became the industry standard for peptide and protein separations. The large pores of the 300 Å TP silica give polypeptide molecules complete access to the interior of the silica pores.

Supplier: WATERS
Description: These columns are suitable for a diverse range of analytes. With mobile phase (pH 1 to 12) and temperature (80 °C) compatibility, this trifunctionally-bonded alkyl column is a universal method development tool that can impact the retention, selectivity and sensitivity of ionisable compounds (with mobile phase pH) while delivering low- and high-pH stability for all analyte types.

Supplier: G-Biosciences
Description: Thiophilic adsorption or thiophilic chromatography is a routinely used technique for the low cost, simple purification of immunoglobulins. Thiophilic adsorption was first developed by Porath et al in 1984 and is a group specific, salt-dependent purification technique that has distinct affinity towards immunoglobulins and α2- macroglobulins. The thiophilic adsorption works on the principle that some proteins in high salt are able to bind to an immobilised ligand that contains a sulfone group in proximity to a thioether group. The bound proteins are then eluted in decreasing salt concentrations. The thiophilic resin binds immunoglobulins, including IgG, IgY and IgM, from serum, ascites or tissue culture supernatants and the purified immunoglobulins are then eluted in a near neutral aqueous buffer.

Supplier: CAMAG
Description: Ideal instrument for exact cutting of TLC/HPTLC plates that are frequently used in method development and pre-testing. The smartCut can cut glass plates up to 3 mm in thickness without damaging the sensitive layer.

Catalog Number: (85193-100ML)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Silver nitrate along with iodine are among several inorganic substances used to induce colour in microscopical preparations. Silver nitrate as a biological stain exploits the strong colors of colloidal metallic silver. Silver nitrate is an important component of the silver staining that is used for the detection of proteins separated by polyacrylamide gel electrophoresis. Silver nitrate is a component of the silver stain kit. It is required for image development in diamine as well as non-diamine silver staining.
UOM: 1 * 100 mL

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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