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Description: The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
Catalog Number: BOSSBS-9461R-A555
UOM: 1 * 100 µl
Supplier: Bioss


Description: Disposable pipettes made from clear polystyrene (PS).
Catalog Number: RATI3110011
UOM: 1 * 200 items
Supplier: RATIOLAB

Description: 3M™ General-Purpose Vinyl Tape 764 is used for all non-critical applications, including colour-coding, bundling, and safety marking.
Catalog Number: MMMA764IO50IW
UOM: 1 * 12 Roll
Supplier: 3M


Description: The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
Catalog Number: BOSSBS-9461R-HRP
UOM: 1 * 100 µl
Supplier: Bioss


Description: Epoxy-coated steel wire, autoclavable.
Catalog Number: 525-9135
UOM: 1 * 1 items
Supplier: Bel-Art Products, a Part of SP


Description: Hematoxylin is Gill’s Formulation 2; a nuclear counter stain of blue-violet colour. It is extracted from the heartwood of the logwood tree.
Catalog Number: ICNA0210192225
UOM: 1 * 25 g
Supplier: MP Biomedicals


Description: Soda-lime glass (AR-Glas®).
Catalog Number: 612-5269
UOM: 1 * 12 items
Supplier: DWK Life Sciences


Description: LDPE, translucent, with PP spray cap.
Catalog Number: 215-0417
UOM: 1 * 5 items
Supplier: SciLabware


Description: LDPE wash bottles gives accurate dispensation of liquid.
Catalog Number: AZLOWGW541VTMLA
UOM: 1 * 5 items
Supplier: SciLabware


Description: The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
Catalog Number: BOSSBS-9461R-CY3
UOM: 1 * 100 µl
Supplier: Bioss


Description: Soda-lime glass, class A.
Catalog Number: KAVA632434116719
UOM: 1 * 1 items
Supplier: Kavalier


Description: These microtube racks are made of highly resistant acetal as it will not shatter or stain in contact with most laboratory chemicals.
Catalog Number: SIMPT360-50O
UOM: 1 * 10 items
Supplier: Simport Scientific


Description: Soda lime glass.
Catalog Number: 612-3963
UOM: 1 * 2 items
Supplier: SciLabware


Description: Highly durable waste containers created with the toughest enviroments in mind.
Catalog Number: 129-3985
UOM: 1 * 1 items
Supplier: Rubbermaid Commercial Products


Description: The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
Catalog Number: BOSSBS-9461R-A488
UOM: 1 * 100 µl
Supplier: Bioss


Description: These MultiRack™ Jr. are ideal for use in incubators, refrigerators, freezers, under lab hoods and om benchtops.
Catalog Number: SIMPS610-16O
UOM: 1 * 10 items
Supplier: Simport Scientific


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