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You Searched For: 5-Bromofuro[2,3-b]pyridine


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Product Image-BOSSBS-0758R

Anti-MSH2 Rabbit Polyclonal Antibody

Description: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
Catalog Number: BOSSBS-0758R
UOM: 1 * 100 µl
Supplier: Bioss
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96-Well Comet Slide 1 slide 1 * 1 items

Description: 96-Well Comet Slide 1 slide 1 * 1 items
Catalog Number: TREV4253-096-03
UOM: 1 * 1 items
Supplier: TREVIGEN
Image Unavailable-SHAN172550

SLIDE BASKETS - 30 SLIDES 1 * 30 items

Description: SLIDE BASKETS - 30 SLIDES 1 * 30 items
Catalog Number: SHAN172550
UOM: 1 * 30 items
Supplier: Epredia
Image Unavailable-TREV4800-30-41

TACS Tissue Control Slides 5 slides 1 * 5 items

Description: TACS Tissue Control Slides 5 slides 1 * 5 items
Catalog Number: TREV4800-30-41
UOM: 1 * 5 items
Supplier: TREVIGEN
Image Unavailable-TREV3950-300-02

FLARE Slides 100 slides 1 * 100 items

Description: FLARE Slides 100 slides 1 * 100 items
Catalog Number: TREV3950-300-02
UOM: 1 * 100 items
Supplier: TREVIGEN
Image Unavailable-DIDAPOD066650

Slides, projection objects, set of 4 slides - 50x50mm. 1 * 1 items

Description: Slides, projection objects, set of 4 slides - 50x50mm. 1 * 1 items
Catalog Number: DIDAPOD066650
UOM: 1 * 1 items
Supplier: DIDALAB
Image Unavailable-LEIH3802615

Cardboard slide folder for 20 slides 1 * 72 items

Description: Cardboard slide folder for 20 slides 1 * 72 items
Catalog Number: LEIH3802615
UOM: 1 * 72 items
Supplier: LEICA HISTOLOGY
Image Unavailable-HECH91270200028

SLIDE BOX FOR 50 MICROSCOPE SLIDES 1 * 30 items

Description: SLIDE BOX FOR 50 MICROSCOPE SLIDES 1 * 30 items
Catalog Number: HECH91270200028
UOM: 1 * 30 items
Supplier: GLASWARENFABRIK KARL HECHT
Image Unavailable-SHANB1781

Box, Slide, Plastic red for 25 slides 1 * 1 items

Description: Box, Slide, Plastic red for 25 slides 1 * 1 items
Catalog Number: SHANB1781
UOM: 1 * 1 items
Supplier: Epredia

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Image Unavailable-TREV4252-200-01

COMETASSAY(R) HT SLIDE 10 SLIDES 1 * 10 items

Description: COMETASSAY(R) HT SLIDE 10 SLIDES 1 * 10 items
Catalog Number: TREV4252-200-01
UOM: 1 * 10 items
Supplier: TREVIGEN
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LUNA Cell Counting Slides, 1000 Slides 1 * 1.000 items

Description: LUNA Cell Counting Slides, 1000 Slides 1 * 1.000 items
Catalog Number: MSPPL12003-LG
UOM: 1 * 1.000 items
Supplier: MARKET SOURCE PART PROCESS
Image Unavailable-TREV4253-960-03

96-Well Comet Slide 10 slides 1 * 10 items

Description: 96-Well Comet Slide 10 slides 1 * 10 items
Catalog Number: TREV4253-960-03
UOM: 1 * 10 items
Supplier: TREVIGEN
Image Unavailable-TREV4253-10K-03

96-Well Comet Slide 100 slides 1 * 100 items

Description: 96-Well Comet Slide 100 slides 1 * 100 items
Catalog Number: TREV4253-10K-03
UOM: 1 * 100 items
Supplier: TREVIGEN
Image Unavailable-TREV4253-02K-03

96-Well Comet Slide 20 slides 1 * 20 items

Description: 96-Well Comet Slide 20 slides 1 * 20 items
Catalog Number: TREV4253-02K-03
UOM: 1 * 20 items
Supplier: TREVIGEN
Image Unavailable-SHAN147

HOLDER, SLIDE, 3 1 * 1 items

Description: HOLDER, SLIDE, 3 1 * 1 items
Catalog Number: SHAN147
UOM: 1 * 1 items
Supplier: Epredia

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Image Unavailable-HEWLG1600-24701

SLIDE SUPPORT 1 * 1 items

Description: SLIDE SUPPORT 1 * 1 items
Catalog Number: HEWLG1600-24701
UOM: 1 * 1 items
Supplier: Agilent
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