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Catalog Number: (BOSSBS-7688R-FITC)
Supplier: Bioss
Description: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9504R-CY5.5)
Supplier: Bioss
Description: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9504R-CY3)
Supplier: Bioss
Description: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9504R)
Supplier: Bioss
Description: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7089R-CY7)
Supplier: Bioss
Description: Activates NF-kappa-B via BCL10.Tissue specificity; Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7588R-A647)
Supplier: Bioss
Description: Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-10361R-CY5)
Supplier: Bioss
Description: Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0063R-CY5)
Supplier: Bioss
Description: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Katacalcin is a potent plasma calcium-lowering peptide.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0862R-CY7)
Supplier: Bioss
Description: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
UOM: 1 * 100 µl


Supplier: Biotium
Description: Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.

Catalog Number: (BOSSBS-1570R-CY3)
Supplier: Bioss
Description: Binds to various kinds of negatively charged substances such as heparin, phospholipids and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-1570R-CY7)
Supplier: Bioss
Description: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7089R-A350)
Supplier: Bioss
Description: Activates NF-kappa-B via BCL10.Tissue specificity; Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7089R-A555)
Supplier: Bioss
Description: Activates NF-kappa-B via BCL10.Tissue specificity; Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7089R-CY3)
Supplier: Bioss
Description: Activates NF-kappa-B via BCL10.Tissue specificity; Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9503R)
Supplier: Bioss
Description: This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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