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Image Unavailable-BOSSBS-2097R-HRP

Anti-AGTR1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-2097R-HRP)
Supplier: Bioss
Description: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7547R-CY7

Anti-CPB2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-7547R-CY7)
Supplier: Bioss
Description: This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues; pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 ug/ml. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7547R-CY5.5

Anti-CPB2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7547R-CY5.5)
Supplier: Bioss
Description: This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues; pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 ug/ml. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1850R-A647

Anti-NR3C2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1850R-A647)
Supplier: Bioss
Description: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
UOM: 1 * 100 µl
Image Unavailable-PRSI92-398

Human Recombinant Coagulation factor IX (from Cells)

Catalog Number: (PRSI92-398)
Supplier: ProSci Inc.
Description: Coagulation factor IX（F9), is a member of the peptidase S1 family. It contains two EGF-like domains, a Gla domain and a peptidase S1 domain. It is primarily expressed in the liver and secreted in plasma. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa. Mutations in position 43 and 46 prevents cleavage of the propeptide, mutation in position 93 probably fails to bind to cell membranes, mutation in position 191 or in position 226 prevent cleavage of the activation peptide. Mutations of human F9 can result in thrombophilia and recessive X-linked hemophilia B (HEMB). An X-linked blood coagulation disorder characterized by a permanent tendency to hemorrhage, due to factor IX deficiency. It is phenotypically similar to hemophilia A, but patients present with fewer symptoms. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma.
UOM: 1 * 0,05 mg

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Image Unavailable-BOSSBS-0077R-CY3

Anti-VIP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-0077R-CY3)
Supplier: Bioss
Description: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0077R-HRP

Anti-VIP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0077R-HRP)
Supplier: Bioss
Description: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7709R

Anti-ZMIZ1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7709R)
Supplier: Bioss
Description: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.Tissue specificity:Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1158R-A555

Anti-AGEs Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1158R-A555)
Supplier: Bioss
Description: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 8% of all plasma zinc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0292R-FITC

Anti-BSA Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0292R-FITC)
Supplier: Bioss
Description: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 8% of all plasma zinc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1158R-CY5.5

Anti-AGEs Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1158R-CY5.5)
Supplier: Bioss
Description: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 8% of all plasma zinc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7709R-A350

Anti-RAI17 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-7709R-A350)
Supplier: Bioss
Description: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.Tissue specificity:Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6399R-CY3

Anti-SIPA1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-6399R-CY3)
Supplier: Bioss
Description: GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.Tissue specificity: Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0356R-A647

Anti-NOS3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-0356R-A647)
Supplier: Bioss
Description: Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0356R-A680

Anti-Digoxin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-0356R-A680)
Supplier: Bioss
Description: Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2345R

Anti-PDLIM1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-2345R)
Supplier: Bioss
Description: PDLIM1 is a cytoskeletal protein that may act as an adapter that brings other proteins to the cytoskeleton. PDLIM1 is strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung, and minimally expressed in liver, thymus, kidney, prostate and pancreas. It is not found in the brain, testis, ovary, and peripheral blood leukocytes.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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