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You Searched For: 2,4-Dimethyloxazole-5-carboxylic+acid


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Image Unavailable-BOSSBS-3930R-A680

Anti-CACNA1A/Cav2.1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.
Catalog Number: BOSSBS-3930R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-ABCAAB313763-20UL

Anti-Calcium channel L type DHPR alpha 2 subunit/CACNA2D1 Rabbit Monoclonal Antibody [clone: EPR23267-59]

Description: Anti-Calcium channel L type DHPR alpha 2 subunit/CACNA2D1 Rabbit Monoclonal Antibody [clone: EPR23267-59]
Catalog Number: ABCAAB313763-20UL
UOM: 1 * 20 µl
Supplier: Abcam

New Product


Image Unavailable-BOSSBS-10490R-A750

Anti-CACNA1B N type Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
Catalog Number: BOSSBS-10490R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3932R-CY3

Anti-CACNA1D Rabbit Polyclonal Antibody (Cy3®)

Description: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
Catalog Number: BOSSBS-3932R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3933R

Anti-CACNA1E Rabbit Polyclonal Antibody

Description: Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
Catalog Number: BOSSBS-3933R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-2781R-FITC

Anti-CACNA1G Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Catalog Number: BOSSBS-2781R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-A18613.18

2-Chlorocyclohexanone ≥97% stabilised

Description: Stabilized with calcium carbonate/magnesium oxide
Catalog Number: A18613.18
UOM: 1 * 50 g
Supplier: Thermo Fisher Scientific

MSDS


Image Unavailable-50042.

Indo-1 pentasodium salt ≥95% (by HPLC) fluorescent indicator, for calcium determination

Description: Membrane-impermeant calcium indicator that can be loaded into cells via microinjection or scrape loading.
Catalog Number: 50042.
UOM: 1 * 1 mg
Supplier: Biotium
Image Unavailable-BOSSBS-3933R-A488

Anti-CACNA1E Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
Catalog Number: BOSSBS-3933R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-6675R-CY3

Anti-KCNN4 Rabbit Polyclonal Antibody (Cy3®)

Description: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Catalog Number: BOSSBS-6675R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-6675R-CY5

Anti-KCNN4 Rabbit Polyclonal Antibody (Cy5®)

Description: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Catalog Number: BOSSBS-6675R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9016R-A647

Anti-SERPINH1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Catalog Number: BOSSBS-9016R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-L15518.06

2,3-Dibromofuran 97% stabilised

Description: Stab. with 0.5% calcium carbonate
Catalog Number: L15518.06
UOM: 1 * 5 g
Supplier: Thermo Fisher Scientific

MSDS Certificates


Image Unavailable-59006.

4-Bromo-A-23187 free acid ≥98% (by TLC, NMR) ionophore, for calcium determination

Description: Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2 indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2 to enter cells to quench indicator fluorescence. However, since 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca2 indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.
Catalog Number: 59006.
UOM: 1 * 1 mg
Supplier: Biotium
Image Unavailable-BOSSBS-6675R-A750

Anti-KCNN4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarisation which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Catalog Number: BOSSBS-6675R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-50010.

FLUO-3 pentaammonium salt ≥95% (by TLC) fluorescent indicator, for calcium determination

Description: Fluo-3, pentaammonium is membrane-impermeant, but can be loaded into cells via microinjection or scrape loading.
Catalog Number: 50010.
UOM: 1 * 1 mg
Supplier: Biotium
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