You Searched For: Epredia


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Description: NGF receptor inhibitor
Catalog Number: ENZOBMLEI2580005
UOM: 1 * 5 mg
Supplier: ENZO LIFE SCIENCES


Description: Tyrphostin A9, 98% 1 * 50 mg
Catalog Number: J63058.MF
UOM: 1 * 50 mg
Supplier: Thermo Fisher Scientific

Description: Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-V. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
Catalog Number: PRSI96-593
UOM: 1 * 100 µG
Supplier: ProSci Inc.


Description: Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
Catalog Number: PRSI96-609
UOM: 1 * 100 µG
Supplier: ProSci Inc.


Description: Tyrphostin A9, 98% 1 * 100 mg
Catalog Number: J63058.MC
UOM: 1 * 100 mg
Supplier: Thermo Fisher Scientific

Description: CD80 (B7-1) 1 * 50 µG
Catalog Number: INSI11-0801-81
UOM: 1 * 50 µG
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD86 (B7-2) 1 * 50 µG
Catalog Number: INSI14-0862-81
UOM: 1 * 50 µG
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD80 (B7-1) 1 * 50 µG
Catalog Number: INSI13-0801-81
UOM: 1 * 50 µG
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD86 (B7-2) 1 * 25 µG
Catalog Number: INSI13-0869-80
UOM: 1 * 25 µG
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD86 (B7-2) 1 * 0,1 mg
Catalog Number: INSI14-0869-82
UOM: 1 * 0,1 mg
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD86 (B7-2) 1 * 0,1 mg
Catalog Number: INSI15-0862-82
UOM: 1 * 0,1 mg
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD80 (B7-1) 1 * 0,5 mg
Catalog Number: PBLBPBL22700-1
UOM: 1 * 0,5 mg
Supplier: PBL BIOMEDICAL LAB


Description: CD86 (B7-2) 1 * 0,5 mg
Catalog Number: PBLBPBL22705-1
UOM: 1 * 0,5 mg
Supplier: PBL BIOMEDICAL LAB


Description: CD86 (B7-2) 1 * 25 Tests
Catalog Number: INSI12-0869-71
UOM: 1 * 25 Tests
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD80 (B7-1) 1 * 50 µG
Catalog Number: INSI12-0801-81
UOM: 1 * 50 µG
Supplier: INSIGHT BIOTECHNOLOGY


Description: CD80 (B7-1) 1 * 25 Tests
Catalog Number: INSI11-0809-71
UOM: 1 * 25 Tests
Supplier: INSIGHT BIOTECHNOLOGY


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