Description: Thermo Scientific Pierce DTSSP is a popular water-soluble crosslinker that contains amine-reactive NHS-ester ends around an 8-atom spacer arm, whose central disulfide bond can be cleaved with reducing agents.

Catalog Number: PIER21565

UOM: 1 * 1 g

Supplier: Thermo Fisher Scientific

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Description: AAT Bioquest's iFluor® dyes are optimized for labeling proteins, in particular, antibodies.

Catalog Number: AATB71500

UOM: 1 * 5 mg

Supplier: AAT BIOQUEST

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Description: Single isomers of ROX are increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purifications that are often required in bioconjugations.

Catalog Number: AATB391

UOM: 1 * 100 mg

Supplier: AAT BIOQUEST

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Description: NHS fluorescein [(5/6-carboxyfluorescein succinimidyl ester), mixed isomer] is an amine reactive derivative of fluorescein dye for antibodies and other probes in fluorescence microscopy, flow cytometry, and immunofluorescence based assays such as western blotting and ELISA.

Catalog Number: PIER46410

UOM: 1 * 100 mg

Supplier: Thermo Fisher Scientific

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Description: An amine-reactive building block for developing a probe that can be recognized by anti-DNP antibodies; Also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

Catalog Number: AATB2021

UOM: 1 * 25 mg

Supplier: AAT BIOQUEST

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Description: Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.

Catalog Number: PIERA35393

UOM: 1 * 10 mg

Supplier: Thermo Fisher Scientific

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Description: <i>In vivo</i> fluorescence imaging uses a sensitive camera to detect fluorescence emission from fluorophores in whole-body living small animals.

Catalog Number: AATB71529

UOM: 1 * 5 mg

Supplier: AAT BIOQUEST

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Description: Thermo Scientific Pierce EMCS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).

Catalog Number: PIER22308

UOM: 1 * 50 mg

Supplier: Thermo Fisher Scientific

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Description: Thermo Scientific Pierce LC-SDA (NHS-LC-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 12.5Å spacer arm separates the two photoreactive groups.

Catalog Number: PIER26168

UOM: 1 * 50 mg

Supplier: Thermo Fisher Scientific

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Description: Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.
Reacts with primary amines and sulfhydryl groups.

Catalog Number: 573114-100

UOM: 1 * 100 mg

Supplier: Merck Millipore (Calbiochem‎)

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Description: 5-FAM-X, SE contains the aminohexanoyl spacer (known as 'X') between the FAM fluorophore and the succinimidyl ester.

Catalog Number: AATB119

UOM: 1 * 5 mg

Supplier: AAT BIOQUEST

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Description: 5-CR6G, SE is amine-reactive derivative of 5-CR6G.

Catalog Number: AATB345

UOM: 1 * 5 mg

Supplier: AAT BIOQUEST

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Description: Thermo Scientific Pierce LC-SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long cyclohexane-stabilized spacer arm (16.2 angstroms).

Catalog Number: PIER22362

UOM: 1 * 50 mg

Supplier: Thermo Fisher Scientific

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Description: Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).

Catalog Number: PIER22322

UOM: 1 * 50 mg

Supplier: Thermo Fisher Scientific

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Description: Thermo Scientific Pierce LC-SPDP is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Catalog Number: PIER21651

UOM: 1 * 50 mg

Supplier: Thermo Fisher Scientific

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Description: Although FITC is still the most popular fluorescent labeling dye for preparing green fluorescent bioconjugates, there are certain limitations with FITC, such as severe photobleaching for microscope imaging and pH-sensitive fluorescence.

Catalog Number: AATB71503

UOM: 1 * 5 mg

Supplier: AAT BIOQUEST

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