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Image Unavailable-BOSSBS-1422R-HRP

Anti-MRP4/ABCC4 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Catalog Number: (BOSSBS-1422R-HRP)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4698R-CY5.5

Anti-EBNA 3B Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-4698R-CY5.5)
Supplier: Bioss
Description: May be involved in transcriptional regulation of both viral and cellular genes by interacting with the host DNA-binding protein RBPJ.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13743R

Anti-CTNNA3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13743R)
Supplier: Bioss
Description: The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7907R-CY5.5

Anti-CLK2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-7907R-CY5.5)
Supplier: Bioss
Description: CDC-like kinase 2 (CLK2) belongs to a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases), which have been shown to phosphorylate serine- and arginine-rich (SR) proteins of the spliceosomal complex, and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the CLK2 proteins affect organismal features such as development, behavior, reproduction, and aging as well as cellular features such as the cell cycle, apoptosis, the DNA replication checkpoint, and telomere length.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7907R-CY3

Anti-CLK2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7907R-CY3)
Supplier: Bioss
Description: CDC-like kinase 2 (CLK2) belongs to a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases), which have been shown to phosphorylate serine- and arginine-rich (SR) proteins of the spliceosomal complex, and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the CLK2 proteins affect organismal features such as development, behavior, reproduction, and aging as well as cellular features such as the cell cycle, apoptosis, the DNA replication checkpoint, and telomere length.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5276R

Anti-CAMK2B Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5276R)
Supplier: Bioss
Description: Ca2+/CalmodulinDependent Protein Kinase II (CaM Kinase II) is a multifunctional calcium and calmodulindependent protein kinase that mediates cellular responses to a wide variety of intercellular signals. CaM Kinase II has been shown to regulate diverse cellular functions including synaptic plasticity, neurotransmitter synthesis and release, gene expression, ion channel function, carbohydrate metabolism, cytoskeletal function, and Ca2+homeostasis. Phosphorylation of Thr286 on the kinase produces an autonomously active form of CaM Kinase II. Autophosphorylation of Thr305 inhibits the activity CaM Kinase II. Phosphorylation at this site appears to reduce the association of CaM Kinase II with the PSD and reduce LTP and learning.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12406R-CY5

Anti-SNX4 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-12406R-CY5)
Supplier: Bioss
Description: SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6028R-CY7

Anti-FCGR3A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-6028R-CY7)
Supplier: Bioss
Description: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6028R-CY5.5

Anti-FCGR3A Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-6028R-CY5.5)
Supplier: Bioss
Description: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4826R-A680

Anti-CD83 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-4826R-A680)
Supplier: Bioss
Description: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4826R-A647

Anti-CD83 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-4826R-A647)
Supplier: Bioss
Description: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10162R-CY3

Anti-ALDH1A1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-10162R-CY3)
Supplier: Bioss
Description: Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7009R

Anti-SART3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7009R)
Supplier: Bioss
Description: RelevanceSART3 regulates Tat transactivation activity through direct interaction. It may be a cellular factor for HIV1 gene expression and viral replication.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7144R

Anti-ARHGEF18 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7144R)
Supplier: Bioss
Description: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0186R-CY3

Anti-IRS3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-0186R-CY3)
Supplier: Bioss
Description: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0186R-FITC

Anti-IRS3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0186R-FITC)
Supplier: Bioss
Description: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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