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Product Image-CORN3558

Disposable aseptic transfer cap for disposable spinner flask, Corning®

Supplier: Corning
Description: These disposable Corning® spinner flask aseptic transfer caps will both reduce contamination and enhance the productivity of your cell culture operations when adding or removing medium and cells.

Certificates

Product Image-710-2028

Listeria swab

Supplier: HYSERVE
Description: Listeria Swab is designed to minimise the risk of contamination of work areas or finished products by <i>Listeria spp</i>. in particular <i>L.monocytogenes</i>. Each self-contained peel pouch consists one green-capped plastic shaft with calcium alginate tip and one labeled and sealed tube containing selective culture medium with indicator. Listeria Swab is sterilised by irradiation.

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Product Image-STMC78061

Mouse Recombinant Noggin

Supplier: STEMCELL Technologies
Description: Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family. Noggin supports maintenance of undifferentiated human embryonic stem cells cultured in mouse embryonic fibroblast (MEF)-conditioned medium (Chaturvedi <i>et al.</i>), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba <i>et al.</i>). Noggin is essential for development of ectodermal structures including neural tube, tooth, hair follicle, and eye, as well as patterning of mesodermal somites and skeletal structures. It also influences chondrogenesis, osteogenesis, and joint formation (Krause <i>et al.</i>).

Product Image-521-3448

Bench top centrifuges and packages, Multifuge X1 and X1R Pro

Supplier: Thermo Scientific
Description: Ergonomically designed, the Thermo Scientific™ Multifuge X1/X1R Pro series of bench top centrifuges have a touch screen interface that enables easier programming for quicker results, and the ability to access and track all runs, rotor life and centrifuge health information for maximum versatility and power at every turn.

Product Image-OHAU30400067

Accessories for platforms and adjustable bars for analogue/digital and reciprocating shakers

Supplier: OHAUS
Description: Universal platforms: Ideal for mounting flask clamps, test tube racks, and bottle clamps. The two-tier braces allow stacking of platforms with a 25,4 cm clearance (available for select sizes). An optional non-skid rubber mat can be placed on the platform for an added non-slip surface. The platform is constructed of type 304 stainless steel.

Image Unavailable-HYCPSH30651.07

Two-dimensional BioProcess Container™ system, Productainer™ BPC bags

Supplier: THERMO BIOPROCESS DIVISION
Description: BioProcess Container™ (BPC™) systems include two- and three-dimensional single-use bags for packaging, storage and transport of 50 to 200 litre volumes of media. Manufactured from medical-grade plastics (cGMP compliant) and configured with ports, tubing and fittings, BPC™ systems provide an efficient means for sterile liquid handling in research and production settings.

Product Image-KIMA21820

Urine container, with collection device for vacuum test tubes

Supplier: KIMA SAS DI CHIARIN RENZO
Description: Sterile containers for urine culture or non sterile for physical chemical microscopic analysis.

Product Image-BRND704575

Accessories

Supplier: Brand
Description: Single-channel aspiration controller, incl. suction tube and three adapters, QuikSip™

Product Image-HEID523-43020-00

Single-channel pump heads

Supplier: Heidolph Instruments GmbH & Co.KG
Description: <B>Peristaltic pump heads SP standard 1,6 mm and SP standard 2,5 mm</B>: For simple pumping tasks. Housing made from die-cast aluminium. Rollers made from stainless steel, roller bearings made from polyamide. Rotor equipped with 2 convex rollers; cell cultures will not be damaged. For tubing with wall thickness of 1,6 or 2,5 mm. Rated flow: 0,5 to 3644 ml/min (depending on the drive and tubing used).

Image Unavailable-MDTC91-200-76

Single-use bags for HYPERStack® vessels

Supplier: Corning
Description: These single-use bags can be connected to tubing via tube welding or by using the pre-assembled multipurpose connectors.

Certificates

Product Image-PRSI96-560

Human recombinant noggin (from HEK293 cells)

Catalog Number: (PRSI96-560)
Supplier: ProSci Inc.
Description: Noggin is also known as NOG, SYM1, SYNS1 and is a secreted homodimeric glycoprotein whose scaffold contains a cystine-knot topology similar to that of BMPs.Secreted Noggin probably remains close to the cell surface due to its binding of heparincontaining proteoglycans.Noggin inhibits TGF-β signal transduction by binding to TGF-β family ligands and preventing them from binding to their corresponding receptors. Noggin plays a key role in neural induction by inhibiting BMP4, along with other TGF-β signaling inhibitors such as chordin and follistatin. Mouse knockout experiments have demonstrated that noggin also plays a crucial role in bone development, joint formation, and neural tube fusion. During embryogenesis, Noggin antagonizes specific BMPs at defined times, for example, during neural tube, somite and cardiomyocyte growth and patterning. During skeletal development, Noggin prevents chondrocyte hyperplasia, thus allowing proper formation of joints. During culture of human embryonic stem cells (hESC) or neural stem cells under certain conditions, addition of Noggin to antagonize BMP activity may allow stem cells to proliferate while maintaining their undifferentiated state, or alternatively, to differentiate into dopaminergic neurons Noggin also appears to maintain adult stem cell populations in vivo, for example, maintaining neural stem cells within the hippocampus.
UOM: 1 * 100 µG
Product Image-HEIP1462080020

Culture media, ready to use, in tubes

Supplier: MERCK LIFE SCIENCE
Description: The current editions of the United States Pharmacopoeia (USP), European Pharmacopoeia (EP) and Japanese Pharmacopoeia (JP) include harmonized methods for the microbiological examination of non-sterile pharmaceutical products. These methods address the total aerobic count (TAMC and TYMC) as well as the test for specified micro-organisms. Harmonized methods facilitate and accelerate the release of pharmaceutical products.

Product Image-PRSI4555

Anti-AMBRA1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI4555)
Supplier: ProSci Inc.
Description: Ambra1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist.
UOM: 1 * 100 µG
Product Image-PRSI4557

Anti-AMBRA1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI4557)
Supplier: ProSci Inc.
Description: Ambra1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist.
UOM: 1 * 100 µG
Image Unavailable-SGRO9035R

Culture media, ready to use, in tubes

Supplier: SOUTHERN GROUP
Description: SGL has a comprehensive range of microbiological media in various formats along with chemicals, stains and reagents for use in a wide range of industries. Every stage of manufacture is carefully controlled.

Product Image-9313005.

Accessories

Supplier: HIRSCHMANN
Description: Base for separate media supply to enable suctioning of the medium directly from a separate storage container using a tube, For: ceramus®/solarus® bottle top dispensers

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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