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Image Unavailable-BOSSBS-5537R-CY5.5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5537R-CY5.5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5544R

Anti-PDPK1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5544R)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5545R-CY5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-5545R-CY5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-MOLE29578582-100G

L-Threonine

Supplier: Molekula
Description: L-Threonine

Image Unavailable-BOSSBS-3275R-A750

Anti-MEK6 Ser207 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-3275R-A750)
Supplier: Bioss
Description: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyses the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15536R-CY7

Anti-ICK Rabbit Polyclonal Antibody (Cy7)

Catalog Number: (BOSSBS-15536R-CY7)
Supplier: Bioss
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl
Image Unavailable-8.14531.0010

(±)-Camphorquinone for synthesis, Sigma-Aldrich®

Catalog Number: (8.14531.0010)
Supplier: Merck
Description: (±)-Camphorquinone for synthesis, Sigma-Aldrich®
UOM: 1 * 10 g

MSDS


Image Unavailable-BOSSBS-5537R-CY5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-5537R-CY5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2739R-CY5.5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2739R-CY5.5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Product Image-0194-01

Lactic acid 85% 85%, BAKER ANALYZED® ACS, J.T.Baker®

Catalog Number: (0194-01)
Supplier: Avantor
Description: The reagent generally available is a mixture of lactic acid (CH₃CHOHCOOH) and lactic acid lactate (C₆H₁₀O₅).
UOM: 1 * 500 mL

Certificates


Image Unavailable-BOSSBS-4123R-CY5

Anti-MAP2K3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-4123R-CY5)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4123R-CY5.5

Anti-MAP2K3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-4123R-CY5.5)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Image Unavailable-BWRLBS4717

Anti-p-Ezrin Rabbit Polyclonal Antibody [clone: T567/Radixin]

Catalog Number: (BWRLBS4717)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human Ezrin, Radixin, Moesin respectively are around the phosphorylation site of Threonine 567, 564, 558.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-4123R-HRP

Anti-MAP2K3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-4123R-HRP)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Image Unavailable-APOSOR6290T-50MG

N-Palmitoyl ceramide

Supplier: Apollo Scientific
Description: A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphate & stimulates ceramide-activated protein kinase.

Image Unavailable-BOSSBS-5777R-A488

Anti-ACVR1C Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5777R-A488)
Supplier: Bioss
Description: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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