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Image Unavailable-BOSSBS-5537R-CY5.5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5537R-CY5.5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-USBI042654

Anti-TBK1 Rabbit Polyclonal Antibody

Catalog Number: (USBI042654)
Supplier: US Biological
Description: Anti-TBK1 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl
Image Unavailable-BOSSBS-5675R-A750

Anti-ROCK2 Thr249 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-5675R-A750)
Supplier: Bioss
Description: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibres and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5674R-A680

Anti-ROCK2 Thr396 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-5674R-A680)
Supplier: Bioss
Description: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibres and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
UOM: 1 * 100 µl
Image Unavailable-BWRLBS4647

Anti-p-AKT Rabbit Polyclonal Antibody [clone: T308]

Catalog Number: (BWRLBS4647)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Threonine 308.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-11484R-HRP

Anti-STK2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11484R-HRP)
Supplier: Bioss
Description: SLK is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11484R-CY7

Anti-STK2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11484R-CY7)
Supplier: Bioss
Description: SLK is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5675R-A647

Anti-ROCK2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-5675R-A647)
Supplier: Bioss
Description: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5675R-A488

Anti-ROCK2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5675R-A488)
Supplier: Bioss
Description: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11990R-CY5

Anti-MAK Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11990R-CY5)
Supplier: Bioss
Description: The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-α and CAB39.
UOM: 1 * 100 µl
Image Unavailable-APOSPC4116-1G

(±)-3,4-Difluoromandelic acid 97%

Supplier: Apollo Scientific
Description: (±)-3,4-Difluoromandelic acid 97%

Image Unavailable-A13349.06

(±)-4-Hydroxy-3-methoxymandelic acid ≥98%

Supplier: Thermo Fisher Scientific
Description: (±)-4-Hydroxy-3-methoxymandelic acid ≥98%

MSDS Certificates

Image Unavailable-BOSSBS-9048R-A680

Anti-TRPM6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-9048R-A680)
Supplier: Bioss
Description: TRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9048R-CY5.5

Anti-TRPM6 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-9048R-CY5.5)
Supplier: Bioss
Description: TRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9318R-A647

Anti-NEK9 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-9318R-A647)
Supplier: Bioss
Description: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9317R-CY7

Anti-NEK9 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-9317R-CY7)
Supplier: Bioss
Description: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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