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Image Unavailable-BOSSBS-8187R-CY5.5

Anti-CSMD2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-8187R-CY5.5)
Supplier: Bioss
Description: The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.
UOM: 1 * 100 µl
Product Image-VACU23110099

Accessories for vario pumps

Catalog Number: (VACU23110099)
Supplier: VACUUBRAND
Description: Vacuum diaphragm pump, Filister head screw M6, stainless steel
UOM: 1 * 1 items
Image Unavailable-BURK0309-2050

Spray head for spray bottles

Supplier: BURKLE
Description: PP spray attachment.

Product Image-1001676.

Accessories for compressed air kit, Airvisor

Catalog Number: (1001676.)
Supplier: HONEYWELL SAFETY
Description: Disposable head and neck cover, pack of 5, Airvisor
UOM: 1 * 5 items
Product Image-PROE8131

Diagonal cutter, oval head

Catalog Number: (PROE8131)
Supplier: PRODUCTION EQUIPMENT
Description: These oval head cutters are ideal for wire harness work and standard printed circuit board assembly.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-11386R-A350

Anti-AADACL3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11386R-A350)
Supplier: Bioss
Description: AADACL3 is a 350 amino acid protein that belongs to the 'GDXG' lipolytic enzyme family and participates in hydrolase activity. Existing as two alternatively spliced isoforms, AADACL3 is encoded by a gene that maps to human chromosome 1p36.21. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9127R-CY7

Anti-CUL7 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-9127R-CY7)
Supplier: Bioss
Description: Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1). An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.
UOM: 1 * 100 µl
Product Image-BUNZ018024

Dust control mop head, dual, synthetic

Catalog Number: (BUNZ018024)
Supplier: BUNZL
Description: The synthetic dual dust control mop head is an essential part of any cleaning kit thanks to its innovative cleaning technology.
UOM: 1 * 1 items
Product Image-CONTSV-3

Swabs for surface validation, CONSTIX® SV-2 / SV-3

Supplier: CONTEC
Description: Sealed knitted polyester swabs for surface cleaning validation.

Image Unavailable-BOSSBS-11015R-FITC

Anti-RPSA Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11015R-FITC)
Supplier: Bioss
Description: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9127R-HRP

Anti-CUL7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-9127R-HRP)
Supplier: Bioss
Description: Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1). An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11387R-A680

Anti-AADACL4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11387R-A680)
Supplier: Bioss
Description: AADACL4 is a 407 amino acid single-pass type II membrane protein belonging to the 'GDXG' lipolytic enzyme family. Integral to the cell membrane, AADACL4 participates in carboxylesterase and hydrolase activities and is encoded by a gene that maps to human chromosome 1p36.22. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9127R-A555

Anti-CUL7 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-9127R-A555)
Supplier: Bioss
Description: Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1). An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11387R-A555

Anti-AADACL4 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11387R-A555)
Supplier: Bioss
Description: AADACL4 is a 407 amino acid single-pass type II membrane protein belonging to the 'GDXG' lipolytic enzyme family. Integral to the cell membrane, AADACL4 participates in carboxylesterase and hydrolase activities and is encoded by a gene that maps to human chromosome 1p36.22. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11387R-CY3

Anti-AADACL4 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11387R-CY3)
Supplier: Bioss
Description: AADACL4 is a 407 amino acid single-pass type II membrane protein belonging to the 'GDXG' lipolytic enzyme family. Integral to the cell membrane, AADACL4 participates in carboxylesterase and hydrolase activities and is encoded by a gene that maps to human chromosome 1p36.22. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5183R-A680

Anti-c-Abl Thr735 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-5183R-A680)
Supplier: Bioss
Description: The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukaemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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