You Searched For: ECONIX+LTD

Catalog Number: (BOSSBS-3730R-A555)

Supplier: Bioss

Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3730R-HRP)

Supplier: Bioss

Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3730R-A680)

Supplier: Bioss

Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

UOM: 1 * 100 µl

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Supplier: ECONIX LTD

Description: These U.N. approved, paper-based containers provide a safe and innovative way to dispose all kinds of waste.

Catalog Number: (PNU041)

Supplier: AIR 7 SEAS TRANSPORT LOGISTICS, INC

Description: VALVE AIR OP LTD 1/2 NC 1 * 1 items

UOM: 1 * 1 items

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Catalog Number: (BSENR-017-500)

Supplier: Biosensis

Description: BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. Post Translation Modification (PTM): The propeptide is N-glycosylated and glycosulfated. PTM: Converted into mature BDNF by plasmin (PLG) (By similarity). DISEASE: Defects in BDNF are a cause of congenital central hypoventilation syndrome (CCHS); also known as congenital failure of autonomic control or Ondine curse. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia. CCHS is frequently complicated with neurocristopathies such as Hirschsprung disease that occurs in about 16% of CCHS cases. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 500 µG

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Catalog Number: (CONNPB2S002LTDA4)

Supplier: CONNECTICUT CLEANROOM

Description: PAPER CLEAN MUNISING LTD A4 85G BLUE 1 * 2.500 items

UOM: 1 * 2.500 items

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Catalog Number: (QUANQTS321)

Supplier: QUANTUM PRODUCTION

Description: Monitor Portable Oxygen EACH Quantum Production Ltd QTS321 1 * 1 items

UOM: 1 * 1 items

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Catalog Number: (QUANQRA440)

Supplier: QUANTUM PRODUCTION

Description: Module Repeater No Display for CO2 Monitor, Quantum Production Ltd QRA440 1 * 1 items

UOM: 1 * 1 items

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Catalog Number: (QUANQLA300)

Supplier: QUANTUM PRODUCTION

Description: Alarm Control Unit LN2 (Battery) Quantum Production Ltd QLA300 1 * 1 items

UOM: 1 * 1 items

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Catalog Number: (QUANQCG200OX)

Supplier: QUANTUM PRODUCTION

Description: Level Gauge, Cleaned for Oxygen Quantum Production Ltd QCG200 OX 1 * 1 items

UOM: 1 * 1 items

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Catalog Number: (QUANQCG240OX)

Supplier: QUANTUM PRODUCTION

Description: Level Gauge, Remote, Cleaned for Oxygen Quantum Production Ltd QCG240 OX 1 * 1 items

UOM: 1 * 1 items

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Catalog Number: (115-2982)

Supplier: GOJO Industries - Europe Ltd

Description: Exceptionally mild, unfragranced foam hand soap.

UOM: 1 * 2 items

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Catalog Number: (115-1947)

Supplier: GOJO Industries - Europe Ltd

Description: A foam hand wash that is gentle to the skin. It provides a creamy and delicate lather.

UOM: 1 * 1 items

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Supplier: GOJO Industries - Europe Ltd

Description: The quat-free GOJO® antimicrobial plus foam hand wash is gentle on skin and formulated to be highly effective.

Catalog Number: (GOJO1904-02-EEU00)

Supplier: GOJO Industries - Europe Ltd

Description: A hygienic hand sanitising foam formulation, proven to help maintain skin health.

UOM: 1 * 1 items

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