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Catalog Number: (ENZOADI905790100)
Supplier: ENZO LIFE SCIENCES
Description: Endothelins are vasoactive peptides that exist in three forms (ET-1, ET-2, and ET-3), and function in the maintenance of vascular tone via two identified seven transmembrane-spanning domain-containing G protein-coupled receptors (GPCR), endothelin A (ETA) and endothelin B (ETB). The human ETA receptor is primarily expressed in vascular smooth muscle cells, including those of the heart (also in myocytes), lung, and brain, and its stimulation generally results in vasoconstriction. Activation of ETA receptors can be stimulated by binding of ET-1 and ET-2, but not ET-3. triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Human ETB receptors are primarily expressed in endothelial cells lining the vessel walls of the lungs, heart, and brain, and in contrast to ETA receptors, stimulation generally results in transient vasodilation. Activation of ETB receptors can be stimulated by binding of all three endothelins, triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Both ETA and ETB receptors signal primarily via coupling to Gq/11 alpha subunits, although Gi/o and Gs coupling are also established mechanisms of endothelin signaling, resulting in stimulation of phospholipases C, A2, and D.
UOM: 1 * 100 µG


Catalog Number: (ABCAAB219358-50)
Supplier: Abcam
Description: Anti-Endothelin A Receptor/ET-A Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (BOSSBS-13096R-A350)
Supplier: Bioss
Description: ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13096R-A488)
Supplier: Bioss
Description: ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13096R-CY5)
Supplier: Bioss
Description: ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13114R-A680)
Supplier: Bioss
Description: ETV3L is a transcriptional regulator, which belongs to the ETS family and contains 1 ETS DNA-binding domain.
UOM: 1 * 100 µl


Catalog Number: (ENZOALX303002M025)
Supplier: ENZO LIFE SCIENCES
Description: Prepared from cerebrosides by a modified protocol of H.E. Carter et al.; J. Lipid Res. 2, 228 (1961).
UOM: 1 * 25 mg


Supplier: Apollo Scientific
Description: Electrophilic reagent for introduction of t-butyldimethylsilyl group. For a review see: Emde et al., Synthesis, 1982 , 1.

Catalog Number: (BOSSBS-0202R-CY7)
Supplier: Bioss
Description: Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13096R-A750)
Supplier: Bioss
Description: ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
UOM: 1 * 100 µl


Catalog Number: (E429-50MG)
Supplier: VWR Chemicals
Description: A competitive and reversible serine protease inhibitor of chymotrypsin, trypsin, kallikrein and plasmin. Not an inhibitor of Factor Xa and thrombin.
UOM: 1 * 50 mg

Catalog Number: (1.02273.0100)
Supplier: Merck
Description: Ammonium cerium(IV) sulphate dihydrate, EMSURE® for analysis, Supelco®
UOM: 1 * 100 g

MSDS


Catalog Number: (0137-1KG)
Supplier: VWR Chemicals
Description: Biological buffers are useful for cell culture <i>in vitro</i>, enzyme assays and some electrophoretic applications at physiological pH.
UOM: 1 * 1 kg

MSDS


Catalog Number: (BOSSBS-13114R-CY5)
Supplier: Bioss
Description: ETV3L is a transcriptional regulator, which belongs to the ETS family and contains 1 ETS DNA-binding domain.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13114R-CY7)
Supplier: Bioss
Description: ETV3L is a transcriptional regulator, which belongs to the ETS family and contains 1 ETS DNA-binding domain.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-13114R-A488)
Supplier: Bioss
Description: ETV3L is a transcriptional regulator, which belongs to the ETS family and contains 1 ETS DNA-binding domain.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
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