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Anti-PDGFRB Mouse Monoclonal Antibody [clone: 42G12]

Catalog Number: (ENZOADI905682100)
Supplier: ENZO LIFE SCIENCES
Description: Mitogenic platelet derived growth factor (PDGF) signaling is mediated by the PDGF tyrosine kinase receptors PDGFRα and PDGFRβ, which exist as homo- or heterodimer isoforms (αα, ββ, αβ). Secretion of PDGFs and expression of PDGFRs in a broad distribution of cell types contributes to regulation of cellular processes including cell growth, actin reorganization, prevention of apoptosis, and chemotaxis. Structurally, the transmembrane PDGFRs are composed of an N-terminal extracellular domain with five immunoglobulin repeats, and an intracellular domain containing two spaced tyrosine kinase domains. PDGF ligands display preferential affinity to PDGFRα and PDGFRβ, with PDGFRβ activation restricted to binding by PDGF BB and PDGF DD. Growth factor binding initiates receptor dimerization and activates the cytosolic tyrosine kinase domains.
UOM: 1 * 100 µG
Product Image-ANTIA95599-100

Anti-PDGF AB + BB Rabbit Polyclonal Antibody

Catalog Number: (ANTIA95599-100)
Supplier: ANTIBODIES.COM
Description: Rabbit polyclonal antibody to PDGF-A for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
UOM: 1 * 100 µG

New Product


Product Image-KWIN100761540L

Industrial coats, Legacy

Supplier: FRISTADS KANSAS
Description: Durable, colour-fast coats made of 65% polyester and 35% cotton, manufactured in LUXE quality.

Image Unavailable-BOSSBS-12157R-A555

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-12157R-A555)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-3872-10ML

Fast Garnet GBC Base solution, Sigma-Aldrich®

Catalog Number: (3872-10ML)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Intended for use in Sigma Procedure 387 for the demonstration of Acid Phosphatase (TRAP).
UOM: 1 * 10 mL
Product Image-SHBT200-58-1MG

Mouse Recombinant PDGF-BB (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation.

Image Unavailable-BOSSBS-0964R

Anti-TRIM32 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-0964R)
Supplier: Bioss
Description: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0964R-CY7

Anti-TRIM32 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0964R-CY7)
Supplier: Bioss
Description: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
UOM: 1 * 100 µl
Image Unavailable-PRSI91-179

Human recombinant PDGF-BB (from E. coli)

Catalog Number: (PRSI91-179)
Supplier: ProSci Inc.
Description: Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-12157R-A350

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-12157R-A350)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12157R-A647

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-12157R-A647)
Supplier: Bioss
Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl
Product Image-342094W

Nuclear Fast Red, Gurr™ for microscopical staining

Catalog Number: (342094W)
Supplier: VWR Chemicals
Description: Nuclear Fast Red, Gurr™ for microscopical staining
UOM: 1 * 25 g

MSDS Certificates


Image Unavailable-BOSSBS-0964R-A555

Anti-TRIM32 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-0964R-A555)
Supplier: Bioss
Description: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
UOM: 1 * 100 µl
Product Image-613-7126

VWR®, Single Channel Pipettes, Mechanical, Fixed Volume

Supplier: VWR Collection
Description: Ergonomically designed to fit large or small hands for extra comfort while working, for left or right handed operation.

5 year warranty

Image Unavailable-201987-100G

Xylene fast yellow 2G 60% (dye content), Sigma-Aldrich®

Catalog Number: (201987-100G)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Acid yellow-17 (C.I. 18965), also known as Disodium 2, 5-dichloro-4-(5-hydroxy-3-methyl-4-(sulphophenylazo)pyrazol-1-yl) benzenesulphonate, and Yellow 2G is an anionic, reactive textile dye. This synthetic azo dye possesses a stable aromatic structure with SO₃H and OH groups. The applications of Acid yellow-17 are seen in detergent, soap, textile, printing, and cosmetic industries.
UOM: 1 * 100 g
Product Image-ROCK200-401-C12

Anti-BB-H32 Rabbit Polyclonal Antibody

Catalog Number: (ROCK200-401-C12)
Supplier: Rockland Immunochemicals
Description: This Protein-A purified antibody has been tested for use in Western blotting and ELISA. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 27.1 kDa in size corresponding to Borrelia burgdorferi p35 Protein by Western blotting.
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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